Shuichiro Mitsuchi¹, Hiroya Naruse^1,2, Masashi Hamada¹, Jun Mitsui^1,2, Wataru Satake¹, Shoji Tsuji³, Tatsushi Toda¹ (1.Department of Neurology, The University of Tokyo Hospital, Japan, 2.Precision Medicine Neurology, Graduate School of Medicine, The University of Tokyo, Japan, 3.Institute of Medical Genomics, International University of Health and Welfare, Japan)

Ryoichi Nakamura¹, Genki Tohnai¹, Naoki Atsuta¹, Daisuke Ito², Masahisa Katsuno², Yuishin Izumi³, Takehisa Hirayama⁴, Osamu Kano⁴, Tomoko Nakazato⁵, Nobutaka Hattori⁵, Rina Hashimoto⁶, Ikuko Aiba⁶, Kazumoto Shibuya⁷, Satoshi Kuwabara⁷, Naoki Suzuki⁸, Masashi Aoki⁸, Masaya Oda⁹, Mitsuya Morita¹⁰, Manabu Doyu¹, Gen Sobue¹, Japanese Consortium for Amyotrophic Lateral Sclerosis research Japanese Consortium for Amyotrophic Lateral Sclerosis research^1,2,3,4,5 (1.Aichi Medical University, Japan, 2.Nagoya University, Japan, 3.Tokushima University, Japan, 4.Toho University, Japan, 5.Juntendo University, Japan, 6.National Hospital Organization Higashinagoya National Hospital, Japan, 7.Chiba University, Japan, 8.Tohoku University, Japan, 9.Vihara Hananosato Hospital, Japan, 10.Jichi Medical University, Japan)

Seiji Emori¹, Kodai Kume², Yoshiaki Nakayama¹, Hideshi Kawakami², Hidefumi Ito¹ (1.Department of Neurology, Wakayama Medical University, Japan, 2.Department of Molecular Epidemiology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan)

Tomohito Kawano¹, Taijun Yunoki¹, Hiroya Naruse², Yumiko Nakano¹, Yuki Taira¹, Chika Matsuoka¹, Yousuke Osakada¹, Emi Nomura¹, Mami Takemoto¹, Ryuta Morihara¹, Toru Yamashita¹, Hiroyuki Ishiura¹ (1.Department of Neurology, Okayama University, Japan, 2.Department of Precision Medicine Neurology, The University of Tokyo, Japan)

Tomoko Yuasa¹, Hiroko Oiwa², Ryouichi Nakamura¹, Naoki Atsuta¹, Junichi Niwa¹, Manabu Douyuu¹ (1.Aichi Medical University Hospital neurology department, Japan, 2.National Center of Neurology and Psychiatry, Japan)

Satoshi Yuki, Rie Ueba, Kaoru Ishizaki, Miki Aritomi, Tomoaki Tezuka (Mitsubishi Tanabe Pharma Corporation, Japan)