[NFS-03] Neuroscience Frontier Symposium 03「Co-evolution of imaging and fluid biomarkers toward stratification of neurological disorders」

[NFS-03-1] Biomarkers for Neurodegenerative Diseases

Ruben Smith (Lund University, Sweden)

Ruben Smith is associate Professor of Neurology and senior consultant at the Memory Clinic, Skåne University Hospital, Malmö, Sweden. He defended his thesis on preclinical models of Huntington’s Disease in 2007 and has since 2012 been working with clinical positron emission tomography (PET) imaging in Neurodegenerative Disease, focusing primarily on tau and beta-amyloid imaging in Alzheimer’s Disease and dopamine and alpha-synuclein imaging in Parkinson’s Disease. In addition to PET-related work Dr Smith has focused on evaluation and assessment of fluid and other imaging biomarkers as well as cognitive testing for diagnostic and prognostic purposes in Neurodegenerative Disorders.
Dr Smith is heading the PET imaging pipeline of the Swedish BioFINDER Studies. The Swedish BioFINDER Studies encompass in total ~ 4000 deeply phenotyped individuals with Alzheimer’s Disease, Dementia with Lewy bodies, Frontotemporal dementia, Parkinson’s Disease, Multiple System atrophy, as well as controls.