[Pe-028] English Poster Session 028「Parkinsonism and Related disorders: Basic research 2」

[Pe-028-3] Parkinson's disease-linked prosaposin gene mutation affects PGRN trafficking and GCase activity

Ryo Wakamori¹, Yutaka Oji¹, Taku Hatano¹, Mitsuhiro Kitagawa¹, Kentaro Gejima¹, Ayami Okuzumi¹, Shin-ichi Ueno¹, Kahori Shiba-fukushima², Risa Nonaka⁵, Kei-ichi Ishikawa^1,6, Masaya Imoto³, Wado Akamatsu⁶, Nobutaka Hattori^1,4 (1.Department of Neurology, Juntendo University School of Medicine, Japan, 2.Department of drug development for Parkinson's disease, Juntendo University Faculty of Medicine, Japan, 3.Division for Development of Autophagy Modulating Drugs, Juntendo University Faculty of Medicine, Japan, 4.Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science, Japan, 5.Department of Clinical Data of Parkinson's Disease, Graduate School of Medicine, Juntendo University, Japan, 6.Center for Genomic and Regenerative Medicine, School of Medicine, Juntendo University, Japan)