*Hirotaka Asai^1,2, Okubo-Suzuki Reiko^1,2, Kaneko Ryosuke³, Ohkawa Noriaki^1,2,4, Saitoh Yoshito^1,2,4, Ghandour Khaled^1,2, Murayama Emi^1,2, Nishizono Hirofumi⁵, Matsuo Mina⁵, Hirayama Teruyoshi^6,7, Muramatsu Shin-Ichi^8,9, Yagi Takeshi⁶, Inokuchi Kaoru^1,2 (1.Dept. of Biochemistry, Grad. Sch. of Medicine & Pharmaceutical Sciences, Univ. of Toyama, 2.Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Corporation, 3.Bioresource center, Gunma University Graduate School of Medicine, Maebashi, Japan, 4.Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency, Japan, 5.Div. of Animal Exp Lab, Life Sci Res Cen, Univ of Toyama, Toyama, Japan, 6.KOKORO, Frontier Biosci, Univ of Osaka, Osaka, 7.Dept Anatomy and Develop Neurobiol, Tokushima Univ, Tokushima, Japan, 8.Dept. of Medical, Jichi Medical Univ, Tochigi, Japan, 9.Cen. for Gene and Cell Theraoy, The institute of Med Sci, Univ of Tokyo, Tokyo, Japan)

*Shota Nakayama¹, Jun Yokose^1,2,3, Kiriko Choko^1,2, Shuntaro Ohno¹, Kaoru Inokuchi^1,2 (1.Dept. Biochem, Grad Sch Med Pharm Sci., Univ of Toyama, Toyama, Japan, 2.JST CREST, Toyama, Japan, 3.Dept. of Psychiatry, Univ. of Texas Southwestern Medical Center, TX, Dallas, USA)

*Sakura Okada¹, Yuji Ikegaya¹, Takuya Sasaki^1,2 (1.Lab Chem Pharmacol, Grad Sch Pharm Sci, Univ of Tokyo, Tokyo, 2.JST PRESTO, Saitama, Japan)

*Saichiro Yagi¹, Yuji Ikegaya¹, Takuya Sasaki^1,2 (1.Lab Chem Pharmacol, Grad Sch Pharm Sci, Univ of Tokyo, Tokyo, 2.JST PRESTO)

*Kousaku Miyake, Saichiro Yagi, Yuki Aoki, Yuji Ikegaya, Takuya Sasaki (Lab of Chemical Pharmacology, Grad Sch of Pharmaceutical Sciences, The Univ of Tokyo, Tokyo)

*Akinobu Ohba^1,2, Iyo Koyanagi¹, Yuteng Wang¹, Peihsi Wu¹, Yuzuki Mimura¹, Sakthivel Srinivasan¹, Takuma Hosokawa¹, Yoan Cherasse¹, Toshie Naoi¹, Takeshi Sakurai¹, Masanori Sakaguchi¹ (1.International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki, Japan., 2.International Christian University, Mitaka, Tokyo, Japan)

*Hiroyuki Mizuno, Yuji Ikegaya (Lab Chem Pharmacol, Grad Sch Pharm Sci, Univ of Tokyo, Tokyo)

*Akihiro Shimbo¹, Ei-Ichi Izawa², Shigeyoshi Fujisawa¹ (1.Lab. for Systems Neurophysiol., RIKEN CBS, Saitama, Japan, 2.Dept. of Psychology, School of Human Relations, Keio Univ. Tokyo, Japan)

*Yu Shikano¹, Yuji Ikegaya², Takuya Sasaki^2,3 (1.Keio Univ. Sch. of Med, Tokyo, 2.Lab of Chemical Pharmacology, Grad Sch of Pharmaceutical Sciences, The Univ of Tokyo, Tokyo, 3.JST PRESTO, Saitama, Japan)

*Taikai Nagayoshi^1,2, Hotaka Fukushima², Satoshi Kida^1,2 (1.Dept. of Applied Biological Chemistry, Univ. of Tokyo, Tokyo, Japan, 2.Dept. of Bioscience, Tokyo Univ. of Agriculture, Tokyo, Japan)

*Toshiyuki Tanimizu^1,2, Kae Sakurauchi¹, Rie Ishikawa^1,2, Satoshi Kida^1,2 (1.Dep. of Bioscience, Tokyo Univ. of Agriculture, 2.Dept. of Applied Biological Chemistry, Univ. of Tokyo)

*Yu Arihara¹, Ryota Tachibana¹, Satoshi Kida^1,2 (1.Dept. of Bioscience, Tokyo Univ. of Agriculture, 2.Dept. of Applied Biological Chemistry, Univ. of Tokyo)

*Ryosuke Watanabe¹, Satoshi Kida^1,2 (1.Dept. of Bioscience, Tokyo Univ. of Agriculture, 2.Dept. of Applied Biological Chemistry, Univ. of Tokyo)

*Maha Essam Wally, Masanori Nomoto, Kareem Abdou, Kaoru Inokuchi (Department of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.)

*Xiance Ni¹, Ran Inoue², Hisashi Mori² (1.Department of Molecular Neuroscience, Graduate School of Medicine and Pharmaceutical Sciences for Education, University of Toyama, Toyama, Japan, 2.Department of Molecular Neuroscience, Department of Academic Research for medical science, University of Toyama, Toyama, Japan)

*Kareem MahmoudIbrahim Abdou, Kiriko Choko, Mohamed H. Aly, Reiko Suzuki Okubo, Kaoru Inokuchi (Department of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan)

*Ali Mohamed Choucry¹, Kareem Abdou^1,2, Reiko Okubo-Suzuki^1,2, Emi Murayama^1,2, Kaoru Inokuchi^1,2 (1.Department of Biochemistry,Graduate School of Medicine and Biological Sciences,University of Toyama, 2.Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), University of Toyama, Toyama, Japan)

*Mohamed Aly Mostafa, Kareem Abdou, Kaoru Inokuchi (Department of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.)

*Khaled Ghandour^1,2,3, Noriaki Ohkawa^1,2,3, Chi Chung Alan Fung^2,4, Hirotaka Asai^1,2, Yoshito Saitoh^1,2,3, Takashi Takekawa^2,5, Hirofumi Nishizono^2,6, Masaaki Sato^4,7,8, Masamichi Ohkura^7,8, Junichi Nakai^7,8, Yasunori Hayashi^8,9,10, Tomoki Fukai^2,4, Kaoru Inokuchi^1,2 (1.University of Toyama, 2.Japan Science and Technology Agency (JST), CREST, Toyama 930-0194, Japan, 3.JST, PRESTO, University of Toyama, Toyama 930-0194, Japan, 4.RIKEN Center for Brain Science, Hirosawa 2-1, Wako, Saitama 351-0198, Japan, 5.Faculty of Informatics, Kogakuin University, 1-24-2 Nishi-Shinjuku, Shinjuku-ku, Tokyo 163-8677, Japan, 6.Life Sciences Research Center, University of Toyama, Toyama 930-0194, Japan, 7.Graduate School of Sciences and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama 338-8570, Japan, 8.Brain Body System Sciences Institute, Saitama University, Saitama 338-8570, Japan, 9.Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan, 10.RIKEN Brain Science Institute, Hirosawa 2-1, Wako, Saitama 351-0198, Japan)

*Masanori Nomoto¹, Emi Murayama¹, Tatsuya Haga³, Shin-Ichi Muramatsu⁴, Tomoki Fukai^2,3, Kaoru Inokuchi¹ (1.Department of Biochemistry, Faculty of Medicine, Graduate School of Medicine & Pharmaceutical Sciences, University of Toyama, Japan., 2.OIST, Okinawa, Japan, 3.RIKEN CBS, 4.Jichi Medical University, Tochigi, Japan)

*Lizeth Katherine Pedraza Correa¹, Rodrigo Sierra¹, Yuichi Takeuchi^1,2, Gabor Kozak¹, Andrea Peijin¹, Livia Barcsai¹, Antal Berenyi^1,3 (1.Department of Physiology, University of Szeged, Hungary, 2.Department of Neuropharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3.Neuroscience Institute, New York University, New York, New York 10016, USA)

*Vahid Hajali, Sajjad Sahab Negah, Mohammad Amin Khodadadegan, Mahsa Saheb (Mashhad University of Medical Sciences)

*He Chen¹, Shengyuan Xue¹, Yuji Naya^1,2,3 (1.School of Psychological and Cognitive Sciences, Peking University, No. 52, Haidian Road, Haidian District, Beijing 100805, China, 2.IDG/McGovern Institute for Brain Research at Peking University, No. 52, Haidian Road, Haidian District, Beijing 100805, China, 3.Beijing Key Laboratory of Behavior and Mental Health, Peking University, No. 52, Haidian Road, Haidian District, Beijing 100805, China)