Oral

[3O10m-1] Pathology of ALS

Fri. Jul 31, 2020 9:00 AM - 10:00 AM Room 10

*Videos are available throughout the meeting period.

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[3O10m-1-01] Distinct influences of ALS-linked SOD1 mutants on endocytosis: implication of strain type of SOD1 aggregates

*Eiichi Tokuda¹, Miho Tagami¹, Rieko Fujiwara¹, Asuka Eguchi¹, Marklund L. Stefan², Shin-ichi Ono^1,3 (1. Sch Pharm, Nihon Univ, Chiba, Japan, 2. Dept Med Bio Sci, Umea Univ, Umea, Sweden, 3. Dept Neurol, Akiru Municipal Medical Center, Tokyo, Japan)

[3O10m-1-02] Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons

*KAZUHIDE ASAKAWA^1,2,3, Hiroshi Handa¹, Koichi Kawakami^2,3 (1. Dept Chem Biol, Tokyo Medical University, 2. Lab of Mol Dev Biol, NIG, 3. Dept Genet, SOKENDAI)

[3O10m-1-03] SQSTM1 deficiency differently affects ubiquitinated protein dynamics between neural and peripheral tissue cells

Awardees for Travel Award

*Shun Mitsui¹, Masahito Ishiyama¹, Kento Shimakura¹, Kai Sato¹, Suzuka Ono¹, Asako Otomo^1,2, Tetsuro Ishii³, Toru Yanagawa³, Masashi Aoki⁴, Shinji Hadano¹ (1. Dept Mol Life Sci, Tokai Univ Sch of Med, Kanagawa, Japan, 2. Micro/Nano Technology Center, Tokai Univ, Kanagawa, Japan, 3. Facul Med, Univ of Tsukuba, Ibaraki, Japan, 4. Dept Neurol, Tohoku Univ Grade Sch of Med, Sendai, Japan)

[3O10m-1-04] Splicing deregulation without neurodegeneration in knock-in mice carrying the ALS-linked TDP-43^M337V mutation

*Seiji Watanabe¹, Kotaro Oiwa¹, Okiru Komine¹, Akira Sobue¹, Koji Yamanaka¹ (1. Dept Neurosci Pathobiol, RIEM, Nagoya Univ, Nagoya, Japan)

Session information

[3O10m-1] Pathology of ALS

[3O10m-1-01] Distinct influences of ALS-linked SOD1 mutants on endocytosis: implication of strain type of SOD1 aggregates

[3O10m-1-02] Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons

[3O10m-1-03] SQSTM1 deficiency differently affects ubiquitinated protein dynamics between neural and peripheral tissue cells

Awardees for Travel Award

[3O10m-1-04] Splicing deregulation without neurodegeneration in knock-in mice carrying the ALS-linked TDP-43^M337V mutation

Authentication

Session information

[3O10m-1] Pathology of ALS

[3O10m-1-01] Distinct influences of ALS-linked SOD1 mutants on endocytosis: implication of strain type of SOD1 aggregates

[3O10m-1-02] Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons

[3O10m-1-03] SQSTM1 deficiency differently affects ubiquitinated protein dynamics between neural and peripheral tissue cells

Awardees for Travel Award

[3O10m-1-04] Splicing deregulation without neurodegeneration in knock-in mice carrying the ALS-linked TDP-43M337V mutation

Authentication

[3O10m-1-04] Splicing deregulation without neurodegeneration in knock-in mice carrying the ALS-linked TDP-43^M337V mutation