F-phenibut (beta-(4-Fluorophenyl)-GABA), a potent GABA<sub>B</sub> receptor agonist, activates an outward rectifying K<sup>+</sup> current and suppresses the generation of action potentials in mouse cerebellar Purkinje cells.

Tomohiko Irie

[2P-038] F-phenibut (beta-(4-Fluorophenyl)-GABA), a potent GABA_B receptor agonist, activates an outward rectifying K⁺ current and suppresses the generation of action potentials in mouse cerebellar Purkinje cells.

*Tomohiko Irie¹, Daiju Yamazaki¹, Makoto Usami¹, Ruri Kikura-Hanajiri² (1.ivision of Pharmacology, National Institute of Health Sciences, Kanagawa, Japan, 2.Division of Pharmacognosy, Phytochemistry, and Narcotics)

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Presentation information

[2P] Ion Channels and Excitable Membranes

[2P-038] F-phenibut (beta-(4-Fluorophenyl)-GABA), a potent GABA_B receptor agonist, activates an outward rectifying K⁺ current and suppresses the generation of action potentials in mouse cerebellar Purkinje cells.

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Presentation information

[2P] Ion Channels and Excitable Membranes

[2P-038] F-phenibut (beta-(4-Fluorophenyl)-GABA), a potent GABAB receptor agonist, activates an outward rectifying K+ current and suppresses the generation of action potentials in mouse cerebellar Purkinje cells.

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[2P-038] F-phenibut (beta-(4-Fluorophenyl)-GABA), a potent GABA_B receptor agonist, activates an outward rectifying K⁺ current and suppresses the generation of action potentials in mouse cerebellar Purkinje cells.