[2P] Depression and Bipolar Disorders

[2P-249] Up-regulation of Pro-protein convertase in the mouse lateral habenula causes depressive-like behaviors through activation of Matrix metalloproteinases

*Hikaru Ito^1,2,3, Nozaki Kanako^3,4, Aizawa Hidenori³ (1.Center for Experimental Animals, Tokyo Medical and Dental University, Tokyo, Japan, 2.Dept Experimental Animal Model for Human Disease, Tokyo Medical and Dental University, Tokyo, Japan, 3.Dept Neurobiology, Hiroshima University, Hiroshima, Japan, 4.Division of Neuroanatomy, Yamaguchi University, Yamaguchi, Japan)