[2P] Disorders of Nervous Systems and Treatment - Others

[2P-255] Neural stem cell-specific Itpa knockout causes depolarization, epileptic seizure and early death in mice

*Daisuke Tsuchimoto¹, Yuichiro Koga¹, Yoshinori Hayashi^2,3, Nona Abolhassani¹, Yasuto Yoneshima¹, Kunihiko Sakumi¹, Hiroshi Nakanishi⁴, Shinya Toyokuni⁵, Yusaku Nakabeppu¹ (1.Div Neurofunc Genomics, MIB, Kyushu Univ, Fukuoka, Japan, 2.Dept Aging Science and Pharmacology, Fac Dental Sci, Kyushu Univ, Fukuoka, Japan, 3.Dept Physiology, Nihon Univ, Sch of Dent, Tokyo, Japan, 4.Dept Pharmacol, Fac Pharmacy, Yasuda Women's Univ, Hiroshima, Japan, 5.Dept Pathol and Biological Responses, Nagoya Univ Grad Sch of Med, Nagoya, Japan)