〇Kosuke Hattori¹, Saeko Ishida¹, Miho Hoshi¹, Jinxi Wang¹, Kazuto Yoshimi^1,2, Tomoji Mashimo^1,2 (1.Division of Animal Genetics, Laboratory Animal Research Center, The Institute of Medical Science, The University of Tokyo, 2.Division of Genome Engineering, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo)