The diabetes medicine metformin ameliorates the exaggerated synaptic release and Munc18-1 accumulation in presynapses of fragile X model mouse neurons

Yukio Sasaki, Renoma Takeda, Rie Ishii, Aki Shiozawa, Terukazu Nogi, Shumaia Parvin

[1P-124] The diabetes medicine metformin ameliorates the exaggerated synaptic release and Munc18-1 accumulation in presynapses of fragile X model mouse neurons

〇Yukio Sasaki¹, Renoma Takeda¹, Rie Ishii¹, Aki Shiozawa¹, Terukazu Nogi¹, Shumaia Parvin¹ (1.Yokohama City University Graduate School of Medical Life Science)

Keywords:developmental disorder, Fragile X syndrome, FMRP, Munc18

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[1P] Neurodevelopmental Disorders

[1P-124] The diabetes medicine metformin ameliorates the exaggerated synaptic release and Munc18-1 accumulation in presynapses of fragile X model mouse neurons

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