[2O12m-1] Memory Improved

[2O12m-1-01] Limb-clasping, cognitive deficit and increased vulnerability to kainic acid-induced seizures in neuronal glycosylphosphatidylinositol deficiency mouse models

〇Lenin C. Kandasamy¹, Mina Tsukamoto¹, Vitaliy Banov^2,3, Sambuu Tsetsegee¹, Yutaro Nagasawa¹, Mitsuhiro Kato⁴, Naomichi Matsumoto⁵, Junji Takeda⁶, Shigeyoshi Itohara², Sonoko Ogawa⁷, Larry J. Young^8,9, Qi Zhang^1,2,8 (1.Laboratory of Social Neural Networks, Center for Social Neural Networks, University of Tsukuba, Tsukuba 305-8577, Japan, 2.Laboratory for Behavioral Genetics, CBS, RIKEN, Wako 351-0198, Japan, 3.Institute of Neuroinformatics, University of Zürich, ETH Zürich, Zürich 8057, Switzerland, 4.Department of Pediatrics, Showa University School of Medicine, Tokyo142-8555, Japan, 5.Department of Human Genetics, Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan, 6.Yabumoto Department of Intractable Disease Research, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan, 7.Laboratory of Behavioral Neuroendocrinology, Faculty of Human Sciences, University of Tsukuba, Tsukuba 305-8577, Japan, 8.Faculty of Human Sciences, Center for Social Neural Networks, University of Tsukuba, Tsukuba 305-8577, Japan, 9.Center for Translational Social Neuroscience, Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, Atlanta GA 30329, USA)

Keywords:Glysosylphosphatidylinositol deficiency, Seizures, Kainic acid, Cognitive deficit