[2O12m-1] 記憶改善

[2O12m-1-01] Limb-clasping, cognitive deficit and increased vulnerability to kainic acid-induced seizures in neuronal glycosylphosphatidylinositol deficiency mouse models

〇Lenin C. Kandasamy¹、Mina Tsukamoto¹、Vitaliy Banov^2,3、Sambuu Tsetsegee¹、Yutaro Nagasawa¹、Mitsuhiro Kato⁴、Naomichi Matsumoto⁵、Junji Takeda⁶、Shigeyoshi Itohara²、Sonoko Ogawa⁷、Larry J. Young^8,9、Qi Zhang^1,2,8 (1.Laboratory of Social Neural Networks, Center for Social Neural Networks, University of Tsukuba, Tsukuba 305-8577, Japan、2.Laboratory for Behavioral Genetics, CBS, RIKEN, Wako 351-0198, Japan、3.Institute of Neuroinformatics, University of Zürich, ETH Zürich, Zürich 8057, Switzerland、4.Department of Pediatrics, Showa University School of Medicine, Tokyo142-8555, Japan、5.Department of Human Genetics, Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan、6.Yabumoto Department of Intractable Disease Research, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan、7.Laboratory of Behavioral Neuroendocrinology, Faculty of Human Sciences, University of Tsukuba, Tsukuba 305-8577, Japan、8.Faculty of Human Sciences, Center for Social Neural Networks, University of Tsukuba, Tsukuba 305-8577, Japan、9.Center for Translational Social Neuroscience, Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, Atlanta GA 30329, USA)

キーワード：Glysosylphosphatidylinositol deficiency, Seizures, Kainic acid, Cognitive deficit