Reduction of MDGA1 in <em>Mdga1<sup>+/-</sup></em> mouse causes impaired hippocampal LTP and memory deficits, those can be rescued by acute administration of D-cycloserine.

Tohru Yamamoto, Daiki Ojima, Atsushi Tada, Yu Tanoue, Naohiro Kurokawa, Takashi Kubota, Hiroo Takahashi, Yasushi Kishimoto, Takashi Tominaga

[2P-017] Reduction of MDGA1 in Mdga1^+/- mouse causes impaired hippocampal LTP and memory deficits, those can be rescued by acute administration of D-cycloserine.

〇Tohru Yamamoto¹, Daiki Ojima¹, Atsushi Tada¹, Yu Tanoue², Naohiro Kurokawa², Takashi Kubota², Hiroo Takahashi¹, Yasushi Kishimoto^2,3, Takashi Tominaga² (1.Fac Med, Kagawa Univ, Kagawa, Japan, 2.Kagawa Sch Pharm Sci, Tokushima Bunri Univ, Kagawa, Japan, 3.Fac Pharm Sci, Teikyo Univ, Tokyo, Japan)

Keywords:E/I balance, MDGA1, Synapse

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Presentation information

[2P] Synapses

[2P-017] Reduction of MDGA1 in Mdga1^+/- mouse causes impaired hippocampal LTP and memory deficits, those can be rescued by acute administration of D-cycloserine.

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Presentation information

[2P] Synapses

[2P-017] Reduction of MDGA1 in Mdga1+/- mouse causes impaired hippocampal LTP and memory deficits, those can be rescued by acute administration of D-cycloserine.

Password

[2P-017] Reduction of MDGA1 in Mdga1^+/- mouse causes impaired hippocampal LTP and memory deficits, those can be rescued by acute administration of D-cycloserine.