[2S09m] RNAs in synaptic physiology and psychiatric diseases

[2S09m-04] Schizophrenia and autism-associated mutations and disrupted m⁶A signal by YTHDF1 cause defects in microtubule function and neurodevelopment

〇Rohini Roy^1,2, Xiangru Li³, Shengqun Hou^1,2, Yoshie Fujiwara¹, Momoe Sukegawa^1,2, Wan-Ting Hong¹, Ikumi Oomoto^1,2, Hidenori Ito⁴, Kandarp Joshi¹, Ruolin Fan ⁵, Koh-ichi Nagata⁴, Kwok-On Lai⁵, Dan Ohtan Wang^1,6,7 (1.Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, 2.Graduate School of Biostudies, Kyoto University, 3.School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, 4.Institute for developmental Research, Aichi Developmental Disability Center, 5.School of Biomedical Sciences, The University of Hong Kong, 6.Wuya College of Innovation, Shenyang Pharmaceutical University, 7.The Keihanshin Consortium for Fostering the Next Generation of Global Leaders in Research (K-CONNEX))

Keywords:Postmitotic Neurodevelopment, m6A RNA modification, Cytoskeletal regulation, Translation