[3O11m-1] Synapse Structural Plasticity

[3O11m-1-01] Presynaptic terminals can sense spine enlargement and mechanical pressure to provide stronger synaptic transmission

〇Hasan UCAR^1,2, Jun NOGUCHI³, Satoshi WATANABE³, Yuichi MORIMOTO^2,1, Sho YAGISHITA^1,2, Noriko TAKAHASHI⁴, Haruo KASAI^1,2 (1.Intl. Res. Ctr. for Neurointelligence (WPI-IRCN), UTIAS, The Univ. of Tokyo, Tokyo, Japan, 2.Grad. Sch. of Medicine, The Univ. of Tokyo, Tokyo, Japan, 3.Natl. Ctr. of Neurol. and Psychiatry, Tokyo, Japan, 4.Dept. of Physiology, Kitasato Univ. Sch. of Med., Tokyo, Japan)

Keywords:mechanosensing and synaptic transmission, SNARE assembly in the active zone in the presynaptic terminal, 2-photon glutamate uncaging and spine enlargement, evoked glutamate release by iGluSnFR