[4P] Neurodegenerative Disorders

[4P-404] Establishment of levodopa-induced dyskinesia mouse model combined with A53T mutant α-synuclein and MPTP treatment by targeting dysfunction of mitochondrial respiration

〇Sung Kyung Yoon^1,2,3, Yunseon Jang^1,2,3, Min Joung Lee^1,2,3, Jiebo Zhu^1,2,3, Changjun Seo^1,2,3, Da Hyun Go^1,2,3, Jun Young Heo^1,2,3 (1.Department of Biochemistry, Chungnam National University School of Medicine, Daejeon, 35015, South Korea, 2.Department of Medical Science, Chungnam National University School of Medicine, Daejeon, 35015, South Korea, 3.Infection Control Convergence Research Center, Chungnam National University School of Medicine, Daejeon, 35015, South Korea)

Keywords:Levodopa-induced dyskinesia, Parkinson's disease, α-synuclein, MPTP