[4P] Autism Spectrum Disorder

[4P-424] Spatial memory deficits in Shank2 mutant mice rescued by enhanced inhibitory synaptic function

〇Yongmin Sung¹, Chae-Seok Lim¹, Nam-Kyung Yu¹, Sukjae Joshua Kang¹, TaeHyun Kim¹, Hyoung-Gon Ko¹, Jung-eun Yang¹, Hyun-Hee Ryu², Taesung Park³, Jungsoo Gim³, Hye Jin Nam⁴, Sung Hee Baek⁴, Stephanie Wegener⁵, Dietmar Schmitz⁵, Tobias M. Boeckers⁶, Min Goo Lee⁷, Eunjoon Kim⁸, Jae-Hyung Lee⁹, Yong-Seok Lee², Bong-Kiun Kaang¹ (1.Laboratory of Neurobiology, School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 08826, Korea, 2.Department of Life Science, Chung-Ang University, Seoul 06974, Korea, 3.Department of Statistics, Seoul National University, Seoul 08826, Korea, 4.Laboratory of Molecular and Cellular Genetics, School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 08826, Korea, 5.Neuroscience Research Center, Cluster of Excellence NeuroCure, Charite, 10117 Berlin, Germany, 6.Institute for Anatomy and Cell Biology, Ulm University, 89081 Ulm, Germany, 7.Department of Pharmacology, Severance Biomedical Science Institute, Yonsei University, Seoul 03722, Korea, 8.Department of Biological Sciences, KAIST, Daejeon 34141, Korea, 9.Department of Life and Nanopharmaceutical Sciences, Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University, Seoul 02447, Korea)

Keywords:Autism spectrum disorder, Shank2, N-methyl-D-aspartate receptor