[4P] Schizophrenia

[4P-431] Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport

〇Shogo Yoshihara¹, Xuguang Xuguang¹, Momo Morikawa², Tadayuki Ogawa¹, Sotaro Ichinose¹, Hirooki Yabe³, Akiyoshi Kakita⁴, Manabu Toyoshima², Yasuto Kunii³, Takeo Yoshikawa², Yosuke Tanaka¹, Nobutaka Hirokawa¹ (1.Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2.Laboratory for Molecular Psychiatry, RIKEN Center for Brain Science, Saitama, Japan, 3.Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, Fukushima, Japan and Department of Psychiatry, 4.Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan)

Keywords:kinesin, betaine, CRMP2 carbonylation, actin dynamics