○CHING PU CHANG^1,4, Yoshifumi YAMAGUCHI ², Masatomo WATANABE³, Tomomi NEMOTO^1,4, Ryosuke ENOKI^1,4 (1. The Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 2. Hokkaido University, ILTS, 3. Fukuyama University, Department of Pharmacy, 4. National Institute for Physiological Sciences)