○Ken Ishikawa¹, Yuta Momono^2,3, Yuki Murakami⁴, Chihiro Yoshida², Yoshitaka Kimura², Yoshiyuki Kasahara², Masatoshi Saito^2,3 (1. Department of Medical Sciences, School of Medicine, Tohoku University, Miyagi, Japan, 2. Department of Maternal and Fetal Therapeutics, Tohoku University Graduate School of Medicine, Miyagi, Japan, 3. Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Miyagi, Japan, 4. Department of Hygiene and Public Health, Kansai Medical University, Osaka, Japan)