○Yoshikazu Nikaido^1,2, Yota Tatara³, Tetsuya Kushikata², Kazuyoshi Hirota^2,4,5 (1. Dept Metabolomics Innov, Grad Sch Med, Hirosaki Univ, Hirosaki, Japan, 2. Dept Anesthesiology, Grad Sch Med, Hirosaki Univ, Hirosaki, Japan, 3. Dept Stress Response Sci, Centr Adv Med Sci, Hirosaki Univ, Grad Sch Med, Hirosaki, Japan, 4. Dept Perioper Med Community Health, Hirosaki Univ, Grad Sch Med, Hirosaki, Japan, 5. Dept Perioper Stress Manag, Hirosaki Univ, Grad Sch Med, Hirosaki, Japan)