○Taishi Kotani¹, Tetsuhiko Mimura^2,3, Shiori Kawase⁴, Aoi William Omi¹, Fumiaki Makiyama^2,3, Hisao Haniu^1,2,5, Taiga Kurihara⁶, Yoshikazu Matsuda⁷, Jun Takahashi³, Naoto Saito⁵, Takeshi Uemura^1,2,4,5 (1. Grad. Sch. of. Sci. & Tech., Shinshu Univ., Nagano, Japan, 2. Grad. Sch. of. Med., Sci. & Tech., Shinshu Univ., Nagano, Japan, 3. Dept of Orthop Surg, Sch of Med, Shinshu Univ., Nagano, Japan, 4. Div. of Gene Res., Res. Cent. for Advanced Sci., Shinshu Univ, Nagano, Japan, 5. IBS-ICCER, Shinshu Univ, Nagano, Japan, 6. Div.Microbiol. & Mol. Cell. Biol. Nihon Pharmaceutical Univ, Saitama, Japan, 7. Div. Clinical Pharmacol., Nihon Pharmaceutical Univ, Saitama, Japan)