[1Pa] Neural Circuit Manipulation

[1Pa-149] An engineered photoactivated adenylyl cyclase optimized for manipulation of presynaptic potentiatio

○Masashi Nagase¹, Takashi Nagashima¹, Shun Hamada², Mieko Morishima¹, Suguru Tohyama¹, Fumiko Arima-Yoshida¹, Tomoha Hirano², Toshihisa Ohtsuka², Ayako M. Watabe¹ (1. Institute of Clinical Medicine and Research, Research Center for Medical Sciences, The Jikei University School of Medicine, 2. Department of Biochemistry, Faculty of Medicine, University of Yamanashi)

Keywords:optogenetics, intracellular signaling, presynaptic targeting, synaptic plasticity