[1Pm] Schizophrenia

[1Pm-115] Pentosidine-accumulating brain pathology in schizophrenia: a preliminary study using patient postmortem brains and non-human primate models

○Hiroaki Ishida^1,2, Kenichi Oshima², Mitsuhiro Miyashita^2,3, Eiichiro Nagata⁴, Izumi Nohara¹, Kensuke Kondo⁵, Kazunari Sekiyama⁶, Mai Kounoe⁶, Yoshinobu Iguchi⁶, Masanari Itokawa^1,2, Makoto Arai^1,2 (1. Schizophrenia Res Project, Tokyo Metro Inst of Med Sci, Tokyo, Japan , 2. Dep Psycihatry, Tokyo Metro Matsuzawa Hosp, Tokyo, Japan, 3. Res Cen for Social Sci & Med, Tokyo Metro Inst of Med Sci, Tokyo, Japan , 4. Dep Neurology, Tokai Univ Sch Med, Kanagawa, Japan, 5. Cen for Basic Tech Res, Tokyo Metro Inst of Med Sci, Tokyo, Japan , 6. Cen for Med Res Co , Tokyo Metro Inst of Med Sci, Tokyo, Japan )

Keywords:Treatment-resistant schizophrenia, Postmortem brains , Macaque monkeys, AGEs (Advanced Glycation End products)