The 46th Annual Meeting of the Japan Neuroscience Society

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Symposia

[1S10a] Frontiers in neuronal homeostasis in aging and neurodegenerative diseases

This symposium was supported by the AMED Strategic Promotion Program for
Translational Research, the Takeda Science Foundation for Pharmaceutical
Research Continuous Grants, and the Tohoku University Young Leaders
Overseas Program.

Tue. Aug 1, 2023 2:00 PM - 4:00 PM Room 10 (Meeting Room 4)

Organizer: Ichiro Kawahata (Department of CNS Drug Innovation, Graduate School of Pharmaceutical Sciences, Tohoku University), David Finkelstein (Parkinson's Disease Laboratory, Florey Institute of Neuroscience and Mental Health, University of Melbourne)

[1S10a-04] Endothelial TFEB signaling-mediated autophagic disturbance initiates microglial activation and cognitive dysfunction

○Ying-Mei Lu1, Ya-Ping Lu1, Xiang Chen2, Xiu-Xiu Liu2, Yi Shi1, Zhao-Cong Wei1, Li-Li Feng2, Quan Jiang3, Wei-Feng Ye4, Takuya Sasaki5, Kohji Fukunaga5, Yong Ji2, Feng Han2 (1. School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China, 2. School of Pharmacy, Nanjing Medical University, Nanjing, China, 3. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China, 4. Department of Pharmacy, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China, 5. Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan)

Keywords:Cognitive dysfunction, Autophagy, Microglia

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