[2Pm] Cerebrovascular Disease and Ischemia

[2Pm-098] Specific KRAS-mutant introduction in the brain endothelial cells causes abnormal vascular tangles related to brain arteriovenous malformation in mice

○Shoji Saito^1,2, Satoshi Miyashita¹, Yuka Nakamura¹, Tokiharu Sato¹, Manabu Natsumeda², Masayasu Okada², Kazuhiro Ando², Tomoaki Suzuki², Hitoshi Hasegawa², Makoto Oishi², Yoshiaki Kubota³, Kazuki Tainaka¹, Yukihiko Fujii², Masaki Ueno¹ (1. System Pathology for Neurological Disorders, Brain Research Institute, Niigata University, Niigata, Japan, 2. Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan, 3. Keio University School of Medicine, Tokyo, Japan)

Keywords:BRAIN ARTERIOVENOUS MALFORMATION, KRAS MUTATION, MOUSE MODEL