[2Pm] Neurodegenerative Disorders

[2Pm-104] Development of ALS/FTLD intervention using oligonucleotide targeting phase separation behavior of FUS

○Mohammad Moniruzzaman¹, Yusuke Fujioka ¹, Akihide Takeuchi ², Akio Masuda ³, Masahiro Neya ⁴, Shinsuke Ishigaki ¹ (1. Molecular Neuroscience Research Center, Shiga University of Medical Science , 2. Dept of Developmental Biol and Func Genomics, Ehime Univ Grad Sch of Med, Japan , 3. Center for Neurological Dis and Cancer, Nagoya Univ Grad Sch of Med, Japan , 4. KNC Laboratories Co., Ltd., Japan )

Keywords:FUS , Antisense oligos , Liquid-liquid phase separation , FUS-ALS/FTLD