[2Pm] Depression and Bipolar Disorders

[2Pm-117] Upregulation of TLR4 and COX-1 by chronic social stress: PET study with a mouse model

○Yumika Motooka^1,6, Ryota Shinohara^1,6, Shiho Kitaoka^1,2,6, Ai Uryu^1,6, Hiroyuki Neyama^3,6, Yi Long Cui^3,6, Tatsuya Kida^4,6, Wakiko Arakaki^4,6, Hisashi Doi^4,6, Yasuyoshi Watanabe^5,6, Tomoyuki Furuyashiki^1,6 (1. Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe, 2. Department of Pharmacology, School of Medicine, Hyogo Medical University, 3. Laboratory for Biofunction Dynamics Imaging, RIKEN Center for Biosystems Dynamics, 4. Laboratory for Labeling Chemistry, RIKEN Center for Biosystems Dynamics, 5. Laboratory for Pathophysiological and Health Scienc, RIKEN Center for Biosystems Dynamics, 6. Japan Agency for Medical Research and Development)

Keywords:STRESS, MICROGLIA, NEUROINFLAMMATION, POSITRON EMISSION TOMOGRAPHY