[2Pm] Molecular, Biochemical and Genetic Techniques

[2Pm-137] Highly selective transgene expression through the flip-excision switch system in adeno-associated virus vector by using a unilateral spacer sequence

○Natsuki Matsushita¹, Shigeki Kato², Nishizawa Kayo², Masateru Sugawara², Kosei Takeuchi³, Yoshiki Miyasaka⁴, Tomoji Mashimo⁵, Kazuto Kobayashi² (1. Div Lab Animal Res, Aichi Med Univ Sch Med, Aichi, Japan, 2. Dep Mol Genet, Inst Biomed Sci, Fukushima Med Univ Sch Med, Fukushima, Japan, 3. Dep Med Cell Biol, Aichi Med Univ Sch Med, Aichi, Japan, 4. Lab Reproductive Eng, Inst Exp Animal Sci, Osaka Univ Med Sch, Suita, Japan, 5. Div Animal Genet, Inst Med Sci, Univ of Tokyo, Tokyo, Japan)

Keywords:adeno-associated viral vector, Cre-loxP recombination, flip-excision switch system, transgene expression