[3O07a-2] Parkinsonism & Related Disorders

[3O07a-2-01] Stress axis dysregulation precedes neurodegeneration in experimental alpha-synuclein-associated Parkinson’s disease.

○Modestos Nakos Bimpos¹, Dionysios Palermos¹, Christine Antoniou¹, Katerina Karali¹, Rafael Stroggilos², Yogesh Singh³, Christiana Mantzourani⁴, Katherine Muksuris¹, Maroula G. Kokotou⁴, Anastasios Delis¹, George Kokotos⁴, Nicolas Casadei³, Olaf Riess³, Leonidas Stefanis^1,5, Alexia Polissidis¹ (1. Center of Clinical, Experimental Surgery and Transnational Research, Biomedical Research Foundation of the Academy of Athens - BRFAA, 11527, Athens, Greece, 2. Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens - BRFAA, 11527, Athens,Greece, 3. Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany, 4. Department of Chemistry, Nationaland Kapodistrian Universityof Athens,11527,Athens, Greece, 5. 1st Department of Neurology, Eginition Hospital, Medical School, National and Kapodistrian University of Athens, 11527,Athens, Greece)

Keywords:Parkinson's Disease, HPA axis, Gut microbiota, Neurodegeneration