[3Pa] アルツハイマー病と認知症

[3Pa-099] Genetic heterogeneity and mutation spectrum of Early-onset Alzheimer's disease in a cohort of Taiwanese patients

○Yung-Hao Ching¹, Liang-Hsuan Hu¹, Chu-Ting Wu², Tai-No Lin¹, Tzu-Yun Hsin¹, Cheng-Jun Lin¹, Hui-Ying x Weng ³, Yen-Ming Liu⁴, Yung-Feng Lin⁴, Shih-Feng Tsai⁴, Raymond Y. Lo⁵ (1. Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien, Taiwan, 2. Department of Medicine, Tzu Chi University, Hualien, Taiwan , 3. Biomedical Industry PhD. The program, National Yang Ming Chiao Tung University, Taipei, Taiwan, 4. Institute of Molecular and Genomic Medicine, National Health Research Institute, Miaoli, Taiwan, 5. Division of Cognitive/Geriatric Neurology, Department of Neurology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan)

キーワード：Early-onset Alzheimer's disease (EOAD), Whole exome sequencing (WES), Mutation spectrum, Digenic