[3Pa] Depression and Bipolar Disorders

[3Pa-114] Chronic social stress alters synaptic central metabolism for prefrontal dysfunction

○Hirotaka Nagai¹, Midori Nagai¹, Chisato Numa¹, Kohei Ota¹, Tomomi Yamashita², Yusuke Kawashima³, Nobuhiko Ohno^4,5, Yosky Kataoka^6,7, Shuichi Shimma^8,9, Yuko Mimori-Kiyosue⁷, Tomoyoshi Soga¹⁰, Tomoyuki Furuyashiki¹ (1. Grad Sch Med, Kobe Univ, Kobe, Japan, 2. Sumitomo Pharma, Osaka, Japan, 3. Kazusa DNA Res Inst, Kisarazu, Japan, 4. Jichi Med Univ, Shimotsuke, Japan, 5. Natl Inst Phys Sci, Okazaki, Japan, 6. RIKEN-JEOL Collaboration Center, Kobe, Japan, 7. RIKEN Center Biosystems Dynamics Res, Kobe, Japan, 8. Grad Sch Engineering, Osaka Univ, Suita, Japan, 9. Osaka Univ Shimadzu Analytical Innovation Lab, Suita, Japan, 10. Inst Adv Biosci, Keio Univ, Tsuruoka, Japan)

Keywords:Social defeat stress, Medial prefrontal cortex, Synapse, Central metabolism