[3Pm] Alzheimer's Disease and Dementia

[3Pm-098] Intravenous administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

○Akiko Amano¹, Nobuo Sanjo¹, Wataru Araki¹, Yasutaka Anraku^2,8, Makoto Nakakido^2,3, Etsuro Matsubara⁴, Tetsuya Nagata^1,5, Kouhei Tsumoto^2,3,6, Takami Tomiyama⁷, Kazunori Kataoka⁸, Takanori Yokota^1,5 (1. Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 2. Department of Bioengineering, School of Engineering, The University of Tokyo, 3. Department of Chemistry & Biotechnology, School of Engineering, The University of Tokyo, 4. Department of Neurology, Oita University, 5. NucleoTIDE and PepTIDE Drug Discovery Center, Tokyo Medical and Dental University, 6. The Institute of Medical Science, The University of Tokyo, 7. Department of Translational Neuroscience, Osaka Metropolitan University Graduate School of Medicine, 8. Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion)

Keywords:Aβ, Alzheimer’s disease, nanomicelle, antibody