[3Pm] Neurodegenerative Disorders

[3Pm-107] Poly-proline-arginine blocked the nucleocytoplasmic transport of axon regeneration factor ATF3 through decreasing Pom121 and Importin β1 interaction

○CHUN-YU LIN^1,2, Tsung-Ping Su⁴, Ru-Huei Fu⁵, Shao-Ming Wang^2,3 (1. School of Medicine, China Medical University, Taichung, Taiwan, 2. Neuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan, 3. Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, 4. Cellular Pathobiology Section, Integrative Neuroscience Research Branch, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, USA, 5. Ph.D. Program for Aging, China Medical University, Taichung, Taiwan)

Keywords:C9orf72-ALS, poly proline-arginine , Pom121, ATF3