The 46th Annual Meeting of the Japan Neuroscience Society

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Training School for Next Generation Scientists

[3TS09a-2] Training School for Next Generation Scientists 8

Thu. Aug 3, 2023 3:00 PM - 4:00 PM Room 9 (Meeting Room 2)

Yuzo Fujino, Mai Horiuchi

Senior Chair: Mariko Miyata (Tokyo Women's Medical University)
Young Chair: Shinya Fujii (Kumamoto University)
Senior Discussant: Shigeo Okabe (The University of Tokyo)

[3TS09a-2-01] FUS suppresses RAN translation and neurodegeneration in C9orf72-linked ALS/FTD through modulating the higher-order structures of GGGGCC repeat RNA

○Yuzo Fujino1,2, Morio Ueyama1, Daisaku Ozawa1, Hayato Ito3, Hideki Taguchi3, Toshiki Mizuno2, Yoshitaka Nagai1,4 (1. Department of Neurology, Kindai University Faculty of Medicine, 2. Department of Neurology, Kyoto Prefectural University of Medicine, 3. School of Life Science and Technology, Tokyo Institute of Technology, 4. Life Science Research Institute, Kindai University)

Keywords:repeat-associated non-AUG translation, C9-ALS/FTD, RNA binding protein, Drosophila

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