[4S05m] Approaching precision medicine: critical cell types and developmental periods of genetically-identifiable neurodevelopmental disorders

[4S05m-01] Pro-myelinating drugs promote functional recovery in an ASD mouse model of Pitt-Hopkins Syndrome.

○Brady J Maher^1,2,3, Joseph F Bohlen¹, Colin M Cleary⁴, Debamitra Das¹, Srinidhi Rao Sripathy¹, Norah L. Sadowski^1,3, Gina Shim¹, Rakaia F. Kenney¹, Ingrid P. Buchler¹, Tapasree Banerji⁵, Thomas S. Scanlan⁵, Daniel K. Mulkey⁴, Alejandra Romero-Morales¹ (1. Lieber Institute for Brain Development, Baltimore, Maryland, USA, 2. Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA , 3. The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA , 4. Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, USA, 5. Department of Physiology & Pharmacology and Program in Chemical Biology, Oregon Health & Science University, Portland, Oregon, USA)

キーワード：autism spectrum disorder, oligodendrocyte, myelination, neurodevelopmental disorder