Fri. Jun 16, 2017 2:10 PM - 4:10 PM Room No.3 (10F Conference Room 1001-1002)

Chair:Kousaku Ohno(Japan Labour, Health and Welfare Organization Sanin Rosai Hospital)

[Aim]
Generally, 50-70% or more of TSC has intellectual impairment, and 30% of which aresevere. Autism is reported to be associated with more than 50% of TSC. ADHD is also combined with 30-50% of TSC, and many suffer from anxiety disorder, mood disorder, and adaptation disorder. Comobid neuropsychosis of TSC patients is collectivelyreferred to tuberous sclerosis complex-associated neuropsychiatric disorders (TAND). The severity of symptoms and what is in need varies among patients and families. The most serious problems of patients and families are self-injuries, impulsive behavior to others, excitement, or insomnia, etc, which are related to TAND. Epileptic seizures may also be aggravated by TAND, sometimes resulting in dangerous conditions. At this symposium, we will clarify the current situation and problems of TAND from the standpoint of clinical practice, basic science, pharmacotherapy, sleep, and epilepsy. We would like to analyze the pathophysiology and build a treatment care system. We are fortunate if we prepare a peaceful time for families who are struggling with difficult situations everyday.