Kentaro Sano¹, MUROFUSHI YUKA², YOKO MORIYAMA², NAOKI ANDOU³, MITSURU IKENO⁴, KEN INOUE⁵, HITOSHI OSAKA⁶, TOMOHIDE GOTO⁷, MASAYUKI SASAKI⁵, KAZUHIRO HAGINOYA⁸, MASAFUMI MORIMOTO⁹, TAKAHITO WADA¹, JUN-ICHI TAKANASHI² (1.The Department of Pediatrics, Tokyo Women's Medical University Yachiyo medical center, Chiba, Japan, 2.The department of pediatric neurology, Tokyo Women's university Yachiyo medical center, Chiba Japan, 3.Josai Kid's clinic, Aichi, Japan, 4.The department of pedeatrics, Juntendo university hospital, Tokyo, Japan)

Hiroya Ono¹, YUUKO MOTOHASHI¹, KAZUSHI MARUO², ERI TAKESHITA¹, TAKASHI SAITO¹, AKIHIKO ISHIYAMA¹, HIROFUMI KOMAKI¹, EIJI NAKAGAWA¹, KENJI SUGAI¹, MASAYUKI SASAKI¹ (1.Department of Child Neurology, National Center of Neurology and Psychiatry, Tokyo, Japan, 2.Faculty of Medicine Research, University of Tsukuba, Ibaraki, Japan)

Yurika Uematsu¹, MITSUGU UEMATSU¹, RYOU SATO^1,2, KEN INOUE³, SHIGEO KURE¹ (1.The Department of Pediatrics, Tohoku University School of medicine, Sendai, Japan, 2.Miyagi children's Hospital, Sendai, Japan, 3.Department of mental retardation and birth defect reserch, national centar of neurology and psychiatry, Kodaira, Japan)

Akihiko Ishiyama^1,2, Yoshihiko Saito¹, Yusaku Miyamoto⁴, Eri Takeshita¹, Yuko Motohashi¹, Takashi Saito¹, Hirofumi Komaki¹, Eiji Nakagawa¹, Kenji Sugai¹, Noriko Sato³, Ichizo Nishino², Masayuki Sasaki¹ (1.Department of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan, 2.Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, 3.Department of Radiology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan, 4.Division of Pediatrics, Kawasaki Municipal Tama Hospital, St. Marianna University School of Medicine, Kanagawa, Japan, 5.The division of pediatric neurology, National Center of Neurology and Psychiatry hospital, Tokyo, Japan)

Takashi Enokizono¹, Nobuyuki Shimozawa², Atsushi Morita¹, Shiena Watanabe¹, Mai Tanaka¹, Tatsuyuki Ohto¹, Kazuhiro Iwama³, Takeshi Mizuguchi³, Naomichi Matsumoto³ (1.Department of Pediatrics, University of Tsukuba Hospital, Ibaraki, Japan, 2.Division of Genomic Research, Life Science Research Center, Gifu University, Gifu, Japan., 3.Department of Human Genetics, Graduate School of Medicine, Yokohama City University, Yokohama, Japan)