ALPS Poster Session 2

[ALPSp2-28] Laser-assisted nanoparticle permeation for promoting the skin absorption and penetration depth of retinoic acid

*Tsong-Long Hwang¹, Woan-Ruoh Lee², Pei-Chi Lo¹ (1. Chang Gung University of Science and Technology, 2. Taipei Medical University)

Two delivery approaches, namely nanoparticles and laser ablation, were combined to improve RA’s absorption efficacy and safety. The nanoparticle absorption enhancement by the lasers was compared between full-ablative (Er:YAG) and fractional (CO₂) modalities. Our results indicated that the laser-mediated nanoparticle delivery provided an efficient and safe use for treating photoaging.