[27H-pm] 構造生物学

Fri. Mar 27, 2020 3:33 PM - 5:09 PM [Room H] Room H (1F)

Chair: Chiaki Nishimura, Nobutada Tanaka

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3:33 PM - 3:45 PM

[27H-pm09S] Screening for crystallization conditions of GATA4 dimerization domain

○Satoshi Shimizu^1,2, Kodai Hara¹, Yoichi Sunagawa^1,2,3, Asami Hishiki¹, Yasufumi Katanasaka^1,2,3, Yusuke Miyazaki^1,2,3, Masafumi Funamoto^1,2, Sari Nurmila¹, Kana Shimizu^1,2, Hiromichi Wada², Koji Hasegawa^2,1, Hashimoto Hiroshi¹, Tatsuya Morimoto^1,2,3 (1. Grad. Pharm. Sci., Univ. of Shizuoka, 2. Div. of Translational Res., Kyoto Medical Center, NHO., 3. Shizuoka General Hospital)

3:45 PM - 3:57 PM

[27H-pm10S] Cryo-EM structure of the signaling complex of the melatonin receptor and Gi protein

○Hiroyuki Okamoto¹, Hirotake Miyauchi¹, Asuka Inoue², Wataru Shihoya¹, Keitarou Yamashita¹, Tsukasa Kusakizako¹, Tomohiro Nishizawa¹, Osamu Nureki¹ (1. School of Science, the University of Tokyo, 2. Grad. Sch. Pharm. Sci., Tohoku Univ.)

3:57 PM - 4:09 PM

[27H-pm11S] Crystal structure of RAD9-RAD1-HUS1-RHINO complex reveals a novel molecular interaction of DNA clamp

○Nao Iida¹, Kodai Hara¹, Hitomi Sakurai¹, Yoshinobu Ishikawa¹, Asami Hishiki¹, Hiroshi Hashimoto¹ (1. Sch. Pharm. Sci., Univ. of Shizuoka)

4:09 PM - 4:21 PM

[27H-pm12S] The Fab portion of immunoglobulin G contributes to its binding to Fc receptor

○Rina Yogo^1,2, Yuki Yamaguchi³, Hiroki Watanabe², Hirokazu Yagi¹, Tadashi Satoh¹, Mahito Nakanishi⁴, Masayoshi Onitsuka⁵, Takeshi Omasa³, Mari Shimada³, Takahiro Maruno³, Tetsuo Torisu³, Shio Watanabe ⁶, Daisuke Higo⁶, Takayuki Uchihashi^2,7, Saeko Yanaka^1,2, Susumu Uchiyama^2,3, Koichi Kato^1,2 (1. Grad. Sch. Pharm. Sci., Nagoya city Univ., 2. ExCELLS, NINS, 3. Grad. Sch. Eng., Osaka Univ., 4. AIST, 5. Grad. Sch. Tech. Indus. Soc. Sci., Tokushima Univ., 6. Thermo Fisher Scientific, 7. Grad. Sch. Phys., Nagoya Univ.)

4:21 PM - 4:33 PM

[27H-pm13] Chemoenzymatic synthesis of completely deuterated cyclodextrin and its application to NMR analysis of glycolipid

○Yoshiki Yamaguchi^1,2, Shino Manabe^2,3, Peter Greimel², Yukishige Ito² (1. Tohoku Med. Pharm. Univ., 2. RIKEN, 3. Grad. Sch. Pharm. Sci., Tohoku Univ.)

4:33 PM - 4:45 PM

[27H-pm14] How internal cavities destabilize a protein

Mengjun Xue¹, Takuro Wakamoto², Camilla Kejlberg³, Yuichi Yoshimura¹, Tania A. Nielsen¹, Michael W. Risør¹, Kristian W. Sanggaard³, ○Ryo Kitahara^2,4, Frans A.A. Mulder¹ (1. Dep. Chem., Univ. Aarhus, 2. Grad. Sch. Life Sci., Ritsumeikan Univ., 3. Dep. Mol. Biol. Gen., Univ. Aarhus, 4. Coll. Pham. Sci., Ritsumeikan Univ.)

4:45 PM - 4:57 PM

[27H-pm15] Contamination of intrinsically disordered proteins widely inhibit amyloid fibril formation of Aβ(1-42) at its nucleation phase

Koki Ikeda¹, Shota Suzuki¹, Yoshiki Shigemitsu², Natsuko Goda¹, Takeshi Tenno^1,4, Atsunori Oshima^1,3, ○Hidekazu Hiroki^1,4 (1. Grad. Sch. Pharm. Sci., Nagoya Univ., 2. Dept. Life Sci. Tech., Tokyo Inst. Tech., 3. CeSPI., Nagoya Univ., 4. BeCellBar, LLC.)

4:57 PM - 5:09 PM

[27H-pm16] Comparison of isomerization reta of amino acids in amyloid beta fragments
Using simultaneous observation of multiple residues real-time ¹H-NMR

○Kenzo Aki¹, Emiko Okamura¹ (1. Pharm.l Sci. Himeji Dokkyo Univ.)

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