[27Z-pm] 医薬品適正使用

Fri. Mar 27, 2020 3:21 PM - 4:57 PM [Room Z] Room 510 (5F)

Chair: Takuya Fujita, Masaki Kobayashi

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3:21 PM - 3:33 PM

[27Z-pm08S] Simultaneous evaluation of metabolic contribution ratio of multiple CYP molecular species by in vitro cocktail method:
Basic study on impact of buffer selection

○Yuta Tamemoto¹, Yukihiro Shibata¹, Shizuka Hozuki¹, Hiromi Sato¹, Akihiro hisaka¹ (1. Grad. Sch. Pharm. Sci., Chiba Univ.)

3:33 PM - 3:45 PM

[27Z-pm09S] Exploring unknown clinical drug-interactions by analyzing adverse event databases in Japan and United States (JADER and FAERS)

○Yukihiro SHIBATA¹, Hiromi SATO¹, Akihiro HISAKA¹ (1. Grad. Sch. Pharm. Sci., Chiba Univ.)

3:45 PM - 3:57 PM

[27Z-pm10] Construction of static drug absorption model (STADAM) systematically integrating in vitro and in vivo parameters

○Akihiro Hisaka¹, Satoshi Asano^1,2, Aoi Yoshitomo¹, Shizuka Hozuki¹, Hiromi Sato¹ (1. Clinical Pharmacology and Pharmacometrics, Grad, Sch. Phar. Sci., Chiba Univ., 2. DMPK Res Dept, Teijin Pharma Limited.)

3:57 PM - 4:09 PM

[27Z-pm11S] Development of in vitro simultaneous evaluation method for P-gp and CYP3A4 activity to predict intestinal availability by using CYP3A4-CPR-HAC/Caco-2 Cells

○Aoi Yoshitomo¹, Satoshi Asano^1,2, Hiromi Sato¹, Yasuhiro Kazuki³, Akihiro Hisaka¹ (1. Grad. Sch. of Pharm. Sci., Chiba Univ., 2. DMPK Res Dept, Teijin Pharma Limited., 3. Chromosome Engineering Res Ctr, Tottori Univ.)

4:09 PM - 4:21 PM

[27Z-pm12S] Solid dispersion system using enteric polymer and pH-modifier to avoid food effect on gastrointestinal absorption of itraconazole

○Yui Suzuki¹, Tatsuki Hirano¹, Yoshiki Seto¹, Hideyuki Sato¹, Satomi Onoue¹ (1. Lab. of Biopharmacy, Univ. of Shizuoka)

4:21 PM - 4:33 PM

[27Z-pm13] Evaluation of membrane permeability and absorbability of cyclic peptides introduced tethers of cyclopropane

○Nanami Katou¹, Mai Uemura¹, Kouhei Matsui², Mizuki Watanabe³, Yoh Takekuma⁴, Satoshi Shuto³, Mitsuru Sugawara^3,4 (1. Sch. Pharm. Sci. Pharm, Hokkaido Univ., 2. Shionogi Co, Ltd., 3. Fac. Pharm. Sci, Hokkaido Univ., 4. Dept. Pharm, Hokkaido Univ. Hosp)

4:33 PM - 4:45 PM

[27Z-pm14] Survey on prescription of direct oral anticoagulants for patients with renal insufficency

○Hiroko Nagae¹, Daiki Hagiwara¹ (1. Fukuoka University Nishijin Hospital Ph.)

4:45 PM - 4:57 PM

[27Z-pm15S] The assosiation between 5-aminosalicylates and TPMT actitivity

○Tenyo Shiba¹, Hiromu Morikubo², Katsuya Otori¹, Taku Kobayashi², Yoichi Tanaka¹ (1. Sch. Pharm, Kitasato Univ., 2. IBD center, Kitasato institute Hospital)

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