The 140th Annual Meeting of the Pharmaceutical Society of Japan (Kyoto)

Session information

Symposium

[S36] Power of natural products 6: Drug development based on natural products from academia

Sat. Mar 28, 2020 9:00 AM - 11:00 AM [Room A] Room A (2F)

Organizers: Sachiko Tsukamoto (Global Cent Nat Res Sci, Grad Sch Pharm Sci, Kumamoto Univ), Masami Ishibashi (Grad Sch Pharm Sci, Chiba Univ)

After the modern era, drug development has been conducted based on natural product chemistry. In 1990s, the chemical libraries containing a large number of compounds prepared through the method of the combinatorial chemistry were constructed, and the high-throughput screening technology using the chemical libraries were enthusiastically expected to afford new medicines from the library. However, only one anticancer agent, Nexavar, has been found from the library and approved for clinical use by FDA. This poor result suggested the limited chemical space covered by products in the combinatorial chemistry, while nature-derived products are substantially, structurally diverse. Although drug discovery from natural sources is based on time-consuming study, a large portion of new pharmaceutical candidates are still originated from natural sources.
In this symposium, three researchers in academia and a coordinator in AMED, involving in drug development from natural sources, plants, microorganisms, and marine organisms, will show their recent progress. The mission and vision of the nature-derived drug development will be discussed.

×

Authentication

Abstracts can be viewed only by pre-registrants from March 5th, 2020.
Enter the password to view the abstracts.


The password will be sent to the pre-registrants by e-mail on March 5th.
Abstracts will be open to the public from March 30th.

×

Please log in with your participant account.
» Participant Log In