[27P02-062] Examination of the antimicrobial activity of C-terminal amide derivatives of myticalin A6 (3-23)-OH

○Keiko Okimura¹, Tamako Shiratori¹, Atsuya Sawada¹, Chinami Katsui¹, Tohru Daikoku¹ (1. Fac. Pharm. Sci., Hokuriku Univ.)

[27P02-063S] Development of helical peptides containing non-proteinogenic amino acids inhibiting VDR-coactivator interaction

○Mami Takyo^1,2, Yuumi Sato^1,2, Hiroaki Ishida³, Keiko Yamamoto³, Takashi Misawa², Yosuke Demizu^1,2 (1. Grad. Sch. Med. Life Sci., Yokohama city Univ., 2. NIHS, 3. Showa Pharm. Univ.)

[27P02-064S] Synthesis and biological evaluation of cinnamoylchromone derivatives as monoamine oxidase inhibitors

○Yuri Takemura¹, Tomoka Aiba², Koichi Takao², Hitoshi Kamauchi², Yoshiaki Sugita² (1. Grad. Sch. Pharm. Sci., Josai Univ., 2. Pharm. Sci., Josai Univ.)

[27P02-065S] Synthesis and biological evaluation of gingerol derivatives as neuroprotective agents

○Takumi Oda¹, Koichi Takao², Hitoshi Kamauti², Yoshiaki Sugita² (1. Grad. Sch. Pharm. Sci., josai Univ, 2. Pharm. Sci., josai Univ)

[27P02-066S] Synthesis and evaluation of selective tumor cell death induction by kukoamine derivatives.

○Asuka Aoyama¹, Koichi Takao², Hitoshi Kamauchi², Yoshiaki Sugita² (1. Grad. Sch. Pharm. Sci., Josai Univ., 2. Pharm. Sci., Josai Univ.)

[27P02-067S] Synthesis of strychnos alkaloid derivatives and evaluation of their cholinesterase inhibitory activity.

○Koki Ueno¹, Hitoshi Kamauchi², Koichi Takao², Yoshiaki Sugita² (1. Grad. Sch. Pharm. Sci., Josai Univ., 2. Pharm. Sci., Josai Univ.)

[27P02-068S] Synthesis and biological evaluation of piperic acid and cinnamic acid derivatives

○Daiki Taki¹, Koichi Takao², Hitoshi Kamauchi², Yoshiaki Sugita² (1. Grad. Sch. Pham. Sci., Josai Univ., 2. Pham. Sci., Josai Univ.)

[27P02-069] Structure-Activity Relationship Study of the Metallo-β-lactamase Inhibitor, ODTAA

○Kiki Nakazato¹, Akari Ikeda^1,2, Akihiro Tomiyama¹, Yoshiki Ikegaya¹, Masako Honsyou², Hiroyuki Asami^1,2, Tomoyasu Hirose^1,2, Toshiaki Sunazuka^1,2 (1. Grad. Sch. Infection Control Sci., Kitasato Univ., 2. Ōmura Inst. Kitasato Univ.)

[27P02-070S] Synthesis and biological evaluation of aromatic polyketide derivatives

○Masafumi Takanashi¹, Hitoshi Kamauchi², Koichi Takao², Yoshiaki Sugita² (1. Grad. Sch. Pharm. Sci., Josai Univ., 2. Pharm. Sci., Josai Univ.)

[27P02-071S] Synthesis of polycyclic pyridone derivatives and their anti-hyphae formation and biofilm formation activity

○Yu Kimura¹, Hitoshi Kamauchi¹, Mikoto Ushiwatari¹, Taishi Seki¹, Koichi Takao¹, Yoshiaki Sugita¹ (1. Pham. Sci., Josai Univ.)

[27P02-072] Discovery of novel isothiourea derivatives as potent dual inhibitors of IDO1 and TDO for cancer immunotherapy

○Naohisa Ogo¹, Masaya Nonaka¹, Momoko Ishihara¹, Mito Watanabe¹, Katsumi Ota¹, Hisashi Murakami¹, Osamu Takikawa², Akira Asai¹ (1. Grad. Div. of Pharma. Sci., Univ. of Shizuoka, 2. AMED)

[27P02-073S] Synthesis and evaluation of antimicrobial fluorine-containing naphthoquinone derivatives

○Ayuka Tatsumi¹, Mitsuaki Yamashita¹, Jun Sawano¹, Ryuji Umeda¹, Yuko Kumeda², Youichi Fukuda¹, Akira Iida¹ (1. Faculty of Agriculture, Kindai Univ., 2. Research Center for Microorganism Control, Osaka Prefecture Univ.)

[27P02-074S] Synthesis of α-methylenecyclopentanones for the development of NFκB inhibitors

○Aya Shiuchi¹, Aki Kohyama¹, Rei Yokoyama¹, Zhou Yue¹, Hiroaki Sakurai¹, Yuji Matsuya¹ (1. Faculty of Pharmaceutical Sciences, University of Toyama)

[27P02-075] Synthesis of 4’-substituted 2’-deoxy-4’-thiocytidines and its Evaluation for Antineoplastic and Antiviral Activities

○Kazuhiro Haraguchi¹, Hiroki Kumamoto¹, Kiju Konno², Hideki Yagi², Yutaka Tatano³, Yuki Odanaka⁴, Satoko Shimbara Mastubayashi⁴, Robert Snoeck⁵, Graciela Andrei⁵ (1. DDepartment of Pharmaceutical Sciences, Nihon Pharmaceutical University, 2. Department of Pharmaceutical Sciences, International University of Health and Welfare, 3. International University of Health and Welfare Department of Pharmaceutical Sciences, School of Pharmacy at Fukuoka, 4. School of Pharmacy, Showa University, 5. Rega Institute for Medical Research, Katholieke Universiteit Leuven)

[27P02-076] Antitumor effects of 6-TMNQ and its derivatives on Colon-26 colon cancer cells

○Yu Jin¹, Aika Ohno¹, Kaho Ono¹, Hiyo Okamoto¹, Haruka Toda¹, Sakura Fuchiwaki¹, Michiko Wada¹, Tetsutaro Kimachi¹, Satoru Takahashi¹ (1. Sch. Pharmcy & Pharm. Sci., Mukogawa Women's Univ.)

[27P02-077S] Structure-activity relationships of SR-12813 for HMG-CoA reductase degradation

○Kota Kawamura¹, Hiromasa Yoshioka², Koji Kuramochi¹, Kenji Ohgane¹ (1. Tokyo Uni. of Science, 2. RIKEN)

Session information

[27P02] 構造活性相関①