[27P02-109] Excitation-transcription coupling is critical for pathophysiological process in vascular smooth muscle cells.

○Suzuki Yoshiaki¹, Takumi Ozawa¹, Nanami Nakajima¹, Yuji Imaizumi¹, Hisao Yamamura¹ (1. Grad. Sch. Pharmaceut. Sci., Nagoya City Univ.)

[27P02-110S] PGE₂ may alter metabolic system in colon cancer cells

○Kiyoka Matsumoto¹, Yuki Nakano¹, Hiroki Takahashi², Yoko Kusuya², Toshihiko Murayama³, Keijo Fukushima¹, Hiromichi Fujino¹ (1. Pharmacol. Life Sci. Grad. Sch. Pharmaceutical Sci., Tokushima Univ., 2. Med. Mycol. Res. Cent., Chiba Univ., 3. Lab. Chem. Pharmacol. Grad. Sch. Pharmaceutical Sci., Chiba Univ.)

[27P02-111S] Biased effects of CRTH2 receptors via PGD₂ and its metabolites

○Nanae Hasuoka¹, Miho Agata¹, Masato Mashimo², Keijo Fukushima¹, Hiromichi Fujino¹ (1. Pharmacol. Life Sci. Faclt. Pharmaceutical Sci., Tokushima Univ., 2. Lab. Pharmacol. Faclt. Pharmaceutical Sci., Doshisha Women's Col. Liberal Arts)

[27P02-112S] Analysis of P-gp and TNF-α gene expression in human skin; focus on BMI

○Riho Takahashi¹, Hiroko Makihara¹, Tomoko Akase¹ (1. Grad.Sch.Med., Yokohama City Univ.)

[27P02-113] Prostaglandin transporter SLCO2A1 regulates hippocampal PGD₂ concentration

○Yoshinobu Nakamura¹, Takeo Nakanishi¹ (1. Faculty of pharmacy, Takasaki University of Health and Welfare, Takasaki, Japan)

[27P02-114] Expression and function of norepinephrine transporter in mammary epithelium

○Takeshi Chiba¹, Tomoji Maeda² (1. Faculty of Pharmaceutical Sciences, Hokkaido University of Science, 2. Department of Clinical Pharmacology and Pharmaceutics, Nihon Pharmaceutical University)

[27P02-115S] Effects of D-cycloserine on social impairment in MDGA1 knockout mice

○shinya matsuzaki¹, Karen Hagi¹, Suzuna Nakazawa¹, Daiki Ojima², Tohru Yamamoto², Kubota Takashi¹, Yasushi Kishimoto^1,3 (1. Kagawa Sch. Pharm. Sci., Tokushima Bunri Univ., 2. Sch. Med. Kagawa Univ., 3. Fac. of Pharma-Sci., Teikyo Univ.)

[27P02-116] Estradiol potentiates the excitatory synaptic transmissions in the rhomboid nucleus of the bed nucleus of the stria terminalis

○Taiju Amano¹, Kiyoshiro Fukui¹, Keiichiro Sato¹, Masabumi Minami¹ (1. Dept Pharmacol, Grad Sch of Pharmaceutical Sci, Hokkaido Univ.)

[27P02-117S] Effects of neural activity of the ventral tegmental area on peripheral immune functions

○Tasuku Kayama¹, Yuji Ikegaya^1,2,3, Takuya Sasaki^1,4 (1. Grad. Sch. Pharm. Sci., Tokyo Univ., 2. Inst. Beyond AI, Tokyo Univ., 3. CiNet, 4. PRESTO)

[27P02-118S] Neuron-specific VPAC2 receptor overexpression leads to cognitive impairment in mice

○Daichi Koan¹, Eiji Imado², Satoshi Asano^1,2, Lu Chen³, Tatsunori Miyaoka³, Mei Yamada³, Kenji Ishimoto^3,4, Shinsaku Nakagawa^3,4, Atsuko Hayata^3,5, Takanobu Nakazawa⁶, Akihiro Harada⁷, Hitoshi Hashimoto^3,5,7,8,9, James Waschek ¹⁰, Yukio Ago^1,2,3,4 (1. Sch. Dent., Hiroshima Univ., 2. Grad. Sch. Biomed. Health Sci., Hiroshima Univ., 3. Grad. Sch. Pharmaceut. Sci., Osaka Univ., 4. Global Ctr., Med. Eng. Inform., Osaka Univ., 5. United Grad. Sch. Child Dev., Osaka Univ., 6. Dept. Biosci., Tokyo Univ. Agr., 7. Grad. Sch. Med., Osaka Univ., 8. Inst. Datability Sci., Osaka Univ., 9. Inst. Open Transdiscip. Res. Initiatives, Osaka Univ., 10. UCLA)

[27P02-119] Wide-band EEG analysis during PTZ-induced seizure in Phf24-KO rats

○Naofumi Kunisawa¹, Hiroaki Hisadumi¹, Masaki Kato¹, Saki Shimizu¹, Kazuaki Sato², Masato Kinboshi¹, Masao Matsuhashi³, Akio Ikeda³, Tadao Serikawa¹, Yukihiro Ohno¹ (1. Osaka Univ. Pharm. Sci., 2. Dept. neurol., Ijinkai takeda general Hosp., 3. Kyoto Univ.)

[27P02-120S] The roles of Vwc2 in food intake and energy metabolism regulation in mice

○Shumpei Miyanishi¹, Kento Onuma¹, Hidenori Fujibayashi¹, Ayumi Miyake¹ (1. Grad. Sch. Pharm Sci., Kyoto Univ.)

Withdrawn

[27P02-121] [Withdrawn]

[27P02-122] A cortical-brainstem circuit facilitates reward-seeking behavior in a conflict environment.

○Natsuko Hitora-Imamura¹, Yuki Honshuku¹, Ryoki Saito¹, Soga Takuji¹, Hiroshi Nomura¹, Masabumi Minami¹ (1. Dep Pharmacol, Grad Sch Pharmaceut Sci, Hokkaido Univ)

[27P02-123] The analysis of paternal expression mechanisms by using MEK1/2 inhibitor U0126

○Yumi Hamasaki¹, Masabumi Minami¹, Taiju Amano¹ (1. Graduate School of Pharmaceutical Sciences, Hokkaido University)

[27P02-124S] The effect of tiliroside on the induction of delayed type hypersensitivity.

○Momoko Otsubo¹, Naohiro Oshima^1,2, Noriyasu Hada¹, Mitsutoshi Tsukimoto¹ (1. Faculty of Pharm. Sci., Tokyo Univ. Sci., 2. Division of Environmental Chemistry, National Institute of Health Sciences)

[27P02-125S] Establishment of IgG-dependent allergy model G-ASDIS and determination of cell types and molecules involved in its induction

○Masato Terashi¹, Kouya Yamaki¹, Yutaka Koyama¹ (1. Laboratory of Pharmacology, Kobe Pharmaceutical University)

[27P02-126S] Effects of extracellular ATP on cytokine production in mouse bone marrow-derived mast cells

○Kosuke Obayashi¹, Kazuki Yoshida¹, Masa-aki Ito¹, isao Matsuoka¹ (1. Takasaki Univ. health and welfare)

[27P02-127] Effect of P2X4 receptor on degranulation of connective tissue-type mast cell

○Kazuki Yoshida¹, Masa-aki Ito¹, Isao Matsuoka¹ (1. Takasaki univ. of health and welfare)

[27P02-128] Risk management of L-Asparaginase-induced allergy: focusing on the influence of concomitant drugs

○Ai Nogami-Hara¹, Yuta Hori¹, Chie Mitsuhata¹, Koji Kajiyama¹, Kentaro Susuki¹, Akira Shimada², Mitsunobu Mio¹ (1. Lab. Pharmacol., Sch. Pharm., Shujitsu Univ., 2. Dept. Pediatr. Hematol. Oncol., Okayama Univ.)

[27P02-129] Screening for food factors and kampo medicines that activate Foxp3 and increase regulatory T cells

○Hiroki Yoshida¹, Hajime Yamato¹, Takuya Ohgi¹, Koushi Rokuta¹, Chihiro Sugita¹, Masahiko Kurokawa¹ (1. Dept. of Biochem., Sch of Pharm., Kyushu Univ. of Health and Welfare.)

[27P02-130] Nephronectin influences EAE development by regulating Th17/Treg balance via reactive oxygen species

○Machiko Honda¹, Yoshiro Saito², Shigeyuki Kon¹ (1. Fac. Pharm. Sci., Fukuyama Univ., 2. Grad. Sch. Pharm. Sci., Tohoku Univ.)

[27P02-131] An approach for evaluating caloric restriction mimetics activity of pharmaceuticals

○Mitsunari Nakajima¹, Shouma Ishikawa¹, Atsushi Sawamoto¹, Satoshi Okuyama¹ (1. College of Pharmaceutical Sciences, Matsuyama Univ.)

[27P02-132S] Studies on mechanisms underlying effects of allergen immunotherapy –Augmentation of interleukin (IL)-10 production from macrophages by the antigen-IgG1 complex–

○Seito Shimizu¹, Masaki Kinoshita¹, Ryoto Nakabayashi¹, Asuka Hirano¹, Masaya Matsuda¹, Kazuyuki Kitatani¹, Takeshi Nabe¹ (1. Fac. of Pharm. Sci., Setsunan Univ.)

[27P02-133S] Therapeutic effects of intratracheal interleukin (IL)-10 administration on severe asthma through inhibition of neutrophil infiltration into the lung

○Ryoto Nakabayashi¹, Masaya Matsuda¹, Seito Shimizu¹, Masaki Kinoshita¹, Asuka Hirano¹, Kazuyuki Kitatani¹, Takeshi Nabe¹ (1. Fac. of Pharm. Sci., Setsunan Univ.)

[27P02-134] Influence of DNA demethylation on NETosis

○Hiroyuki Yasuda^1,2, Kenjiro Matsumoto¹, Shinichi Kato¹, Eisuke Sato² (1. Dept. of Pharmacol. and Exp. Ther., Kyoto Pharm. Univ., 2. Dept. of Biochem., Suzuka Univ. of Med. Sci.)

[27P02-135S] Endothelial cell-specific protein Robo4 suppresses inflammatory diseases and COX-2 expression.

○Miki Matsui¹, Keisuke Shirakura², Ryosuke Ishiba², Yoshiaki Okada², Takefumi Doi² (1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ.)

Session information

[27P02] 薬理学①