[27P02-272S] A Study of Oxidative Stress States on Sleep Disorder

○Hitomi Nishi¹, Yuika Noguchi¹, Kaori Yama¹, Sato Honma², Ken-ichi Honma², Jun Miura^1,2 (1. Faculty of Pharmaceutical Sciences, Depertment of Pharmacy, Hokkaidou University of Science , 2. Sapporo Hanazono Hospital)

[27P02-273S] Study on α-synuclein in sleep disorder

○Yuika Noguchi¹, Hitomi Nishi¹, Kaori Yama¹, Sato Honma², Ken-ichi Honma², Jun Miura^1,2 (1. Faculty of Pharmaceutical Sciences, Department of Pharmacy, Hokkaido University of Science, 2. Sapporo Hanazono Hospital)

[27P02-274] Synergic activation of LPS-HMGB1-stimulated proinflammatory response in RAW264.7 cells by advanced glycation endproducts

○Shuji Mori¹, Masahiro Watanabe¹, Hidenori Wake³, Keyue Liu², Hideo Takahashi³, Masahiro Nishibori², Takao Toyomura¹ (1. Sch parm, Shujitsu Univ, 2. Grad Sch Med Dent Pharm Sci, Okayama Univ, 3. Fac Med, Kindai Univ)

[27P02-275] Effect of combination therapy using two Bcl-2 inhibitors on pancreatic cancer cells

○Yoshihito Morimoto¹, Kimihiko Takada¹, Watanabe Kazuhiro¹, Hirohara Masayoshi¹, Hamamoto Tomoyuki¹, Masuda Yutaka¹ (1. Showa Pharmaceutical Univ.)

[27P02-276] Mechanism of action of the combination of xanthine oxidoreductase (XOR) inhibitor and inosine (ATP enhancer) effective to treat mitochondrial disease and Parkinson’s disease.

○NAOYUKI KAMATANI¹ (1. Research Institute for Artificial Intelligence in Medicine)

[27P02-277] Development and application of screening system for genetic disorders

○Atsuko Takeuchi¹, Chisato Tode¹, Hisahide Nishio² (1. Kobe Pharm. Univ., 2. Kobe Gakuin Univ.)

[27P02-278S] Therapeutic effect of high-level expression of lysocardiolipin acyltransferase in the liver using an improved adenovirus on metabolism in mice fed a high-fat diet

○Tomomi Hase¹, Kahori Shimizu¹, Tomoyoshi Kohama¹, Yudai Muro¹, Ayako Taketomi¹, Fuminori Sakurai², Hiroyuki Mizuguchi^2,3,4,5, Koji Tomita¹, Toru Nishinaka¹ (1. Pharma., Osaka Ohtani Univ., 2. Grad. Sch. of Pharma. Sci., Osaka Univ., 3. Natl. Inst. of Biomed. Innov. Health Nutr., 4. MEIC, Osaka Univ., 5. OTRI, Osaka Univ.)

[27P02-279] Biochanin A ameliorated ER stress-induced leptin resistance

○Keigo Horiuchi¹, Kyoji Tsuchio¹, Goshi Matsushima¹, Thon Mina¹, Toru Hosoi², Koichiro Ozawa¹ (1. Dept. Pharmacotherapy, Grad. Sch. Biomed. Health Sci., Hiroshima Univ., 2. Dept. Clin. Pharmacology, Facul. Pharmaceutical Sci., Sanyo-Onoda City Univ.)

[27P02-280S] Elucidation of inflammation mechanism induced by indoxyl sulfate in macrophage

○Go Kitahara¹, Kazuma Higashisaka^2,3, Nanan Ishida¹, Ryo Isaka², Yuji Sakahashi², Kotoe Kiyomoto², Shintaro Yamaguchi², Rina Izutani¹, Jyundai Kobayashi¹, Hirofumi Tsujino^2,4, Kazuya Nagano², Yasuo Tsutsumi^2,5 (1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ., 3. Grad. Sch. Med., Osaka Univ., 4. Museum, Osaka Univ., 5. MEIC, Osaka Univ.)

[27P02-281S] Amount of phosphorylated TrkB in serum extracellular vesicles reflect ergothioneine-induced enhancement of cognitive function

○Ruri Matsumoto¹, Takahiro Ishimoto¹, Satoshi Matsumoto², Yusuke Masuo¹, Makoto Suzuki², Yukio Kato¹ (1. Fac. Pharm., Kanazawa Univ., Kanazawa, 2. L•S Corporation Co. Ltd)

[27P02-282] Evaluation of the risk for postoperative delirium with hypnotics in hospitalized patients after large intestine resection

○YUKA KATO¹, AKIHIRO MORITSUKA¹, HIROO NAKAGAWA¹, HITOSHI SASAKI¹ (1. Department of Hospital Pharmacy, Nagasaki University Hospital)

[27P02-283] A case in which collaboration between a pharmacist and a child care staff contributedo to improving medication adherenxe for pediatric patients

○Ayaka Uryu¹, Mika Okada¹, Nanami Kantou², Hikari Hanano¹, Shiori Saruta¹, Satomi Narui¹, Momoko Suzuki¹, Kuniyoshi Satou¹, Shinpei Abe³, Hidenori Haruna³, Toshiaki Shimizu³, Ryutaro Arakawa¹ (1. Pharmaceutical department,Juntendo Univ, 2. Pediatrics adolescent department,Juntendo Univ, 3. Faculty of Medicine Pediatrics department,Juntendo Univ)

[27P02-284] Reduced proliferative capacity and altered levels of secreted substances of calcineurin-deficient enteric glial cells in relation to the dysfunction and homeostasis breakdown of the small intestine

Teramoto Hikaru¹, Hirashima Naohide¹, ○Masahiko Tanaka¹ (1. Grad. Sch. Pharmaceut. Sci., Nagoya City Univ.)

[27P02-285] Comparative effectiveness of glycyrrhizin and related compounds in protection against acetaminophen-induced liver injury

○Yasuhiro Masubuchi¹, Sakiko Shingyouchi¹, Miki Sugawara¹, Aki Konno¹, Saki Yoshida¹ (1. Chiba Inst. Sci.)

[27P02-286] Investigation of characteristic of Aquaporins in cerebral ischemia model mice

○Yasuko Tanaka¹, Kaho Kashima¹, Asuka Kaseda¹, Kenichi Ishibashi¹ (1. Meiji Pharmaceutical University)

[27P02-287] Histopathological analysis of vacuolated cells in the spleen and thymus of alloxan diabetic rats

○Yasushi Kodama¹, Shiho Mimura¹, Taiki Kouya¹, Miwa Matsuda², Mayumi Kamigaki¹, Kumatoshi Ishihara¹ (1. Faculty of Pharm. Sci., Hiroshima Int. Univ., 2. Faculty of Health Sci., Hiroshima Int. Univ.)

[27P02-288] In vitro severe heat stroke model using human iPS cells

○Kenji Kawabata^1,2, Kentarou Shimizu³, Misae Nishijima¹, Hiroshi Ogura³, Tomoko Yamaguchi¹ (1. Lab. Stem Cell Reg., Nat. Inst. Biomed. Innov., 2. Grad. Sch. Pharm, Sci., Osaka Univ., 3. Grad. Sch. Med., Osaka Univ.)

[27P02-289S] Effects of dissolved hydrogen on bone remodeling

○Ayako Senota¹, Kazuki Nabatame¹, Rika Hirano¹, Sana Inoue^1,2, Rei Takahashi^1,2 (1. Faculty of Pharmaceutical Sciences Doshisha Women’s College of Liberal Arts, 2. Graduate School of Pharmaceutical Sciences Doshisha Women’s College of Liberal Arts)

[27P02-290S] Analysis of invasive potential of human breast cancer cells using the Matrigel basement membrane model

○Atsumi Fujimoto¹, Yoriko Inuishi¹, Hiroka Matsuda¹, Saya Yamaguchi¹, Sana Inoue^1,2, Rei Takahashi^1,2 (1. Faculty of Pharmaceutical Sciences Doshisha Women’s College of Liberal Arts, 2. Graduate School of Pharmaceutical Sciences Doshisha Women’s College of Liberal Arts)

[27P02-291S] Analysis of ALDH1A3 and Ki-67 expression patterns in human breast cancer cell populations with acquired apoptosis resistance

○Ai Kanzaki¹, Miki Imanishi¹, Sana Inoue^1,2, Rei Takahashi^1,2 (1. Faculty of Pharmaceutical Sciences Doshisha Women’s College of Liberal Arts, 2. Graduate School of Pharmaceutical Sciences Doshisha Women’s College of Liberal Arts)

[27P02-292S] Immunocytochemical analysis of ALDH1A3 expression patterns in human breast cancer cell populations with acquired apoptosis resistance

○miki imanishi¹, Ai Kanzaki¹, Sana Inoue^1,2, Rei Takahashi^1,2 (1. Faculty of Pharmaceutical Sciences Doshisha Women’s College of Liberal Arts, 2. Graduate School of Pharmaceutical Sciences Doshisha Women’s College of Liberal Arts)

[27P02-293] Elucidation of the role of PGRMC1 on induction of ferroptosis

○Kazuma Higashisaka^1,2, Ying Lin¹, Sachiyo Hanamuro³, Kohei Izusawa¹, Hiroto Konishi³, Hirofumi Tsujino^1,4, Kazuya Nagano¹, Yasuo Tsutsumi^1,5 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Med., Osaka Univ., 3. Sch. Pharm. Sci., Osaka Univ., 4. Museum, Osaka Univ., 5. MEIC, Osaka Univ.)

[27P02-294S] Evaluation of Ferroptosis inducer sensitivity in Osimertinib-tolerant cells

○Hiroto Konishi¹, Kazuma Higashisaka^2,3, Ying Lin², Sachiyo Hanamuro¹, Kohei Izusawa², Yuya Haga², Lili Yang², Hirohumi Tsujino^2,4, Kazuya Nagano², Yasuo Tsutsumi^2,5 (1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ., 3. Grad. Sch. Med., Osaka Univ., 4. Museum, Osaka Univ., 5. MEIC, Osaka Univ.)

[27P02-295S] Investigation of the survival mechanism of non-small cell lung cancer under high concentration of EGFR-TKI exposure

○NISHIMURA Akihide¹, Yuya HAGA², Lili YANG², Naoki SEKINE², Yuuki TSUJII¹, Hirofumi TSUJINO^2,3, Kazuya NAGANO², Kazuma HIGASHISAKA^2,4, Yasuo TSUTSUMI^2,5 (1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ., 3. Museum, Osaka Univ., 4. Grad. Sch. Med., Osaka Univ., 5. MEIC, Osaka Univ.)

[27P02-296S] The mechanisms of intrinsic resistance to Dasatinib in triple-negative breast cancer

○Yuya HAGA¹, Kazuma HIGASHISAKA^1,2, Lili YANG¹, Naoki SEKINE¹, Yuki TSUJII³, Akihidie NISHIMURA³, Ying LIN¹, Hirofumi TSUJINO^1,4, Kazuya NAGANO¹, Yasuo TSUTSUMI^1,5 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Med., Osaka Univ., 3. Sch. Pharm. Sci., Osaka Univ., 4. Museum, Osaka Univ., 5. MEIC, Osaka Univ.)

[27P02-297S] Establishment of a new treatment method of PARP inhibitors in triple-negative breast cancer

○Yuuki TSUJII¹, Yuya HAGA², Naoki SEKINE², Lili YANG², Akihide NISHIMURA¹, Hirofumi TSUJINO^2,3, Kazuya NAGANO², Kazuma HIGASHISAKA^2,4, Yasuo TSUTSUMI^2,5 (1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ., 3. Museum, Osaka Univ., 4. Grad. Sch. Med., Osaka Univ., 5. MEIC, Osaka Univ.)

[27P02-298S] Functional analysis of prostaglandine I₂ in the distant metastasis of breast cancer

○Tianqi ZHANG¹, Kazuya NAGANO^1,2, Soshi TERADA¹, Kazumasa HIRATA¹, Hirofumi TSUJINO^1,3, Kazuma HIGASHISAKA^1,2, Yasuo TSUTSUMI^1,2,4 (1. Grad. Sch. Pharm. Sci. Osaka Univ., 2. Grad. Sch. Med. Osaka Univ., 3. Museum, Osaka Univ., 4. MEIC. Osaka Univ.)

[27P02-L003] Analysis of expression patterns of CD24/CD44 and ALDH1A3 in the reconstruction of breast cancer cell populations with acquired apoptosis resistance

○Hinako Homma¹, Moe Fujino¹, Yukie Hirata¹, Saki Matsuda¹, Sana Inoue^1,2, Rei Takahashi^1,2 (1. Faculty of Pharmaceutical Science, Doshisha Woman's college of Liberal Arts, 2. Graduate School of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts)

Session information

[27P02] 病態生理学（臨床生化学）
病態生理学（疾病と遺伝子・遺伝子治療、薬理活性、その他）
病態生理学（病態モデル）
病態生理学（がん）①