[27V03-am] ケミカルバイオロジー①

Sat. Mar 27, 2021 9:00 AM - 10:24 AM [Room V03] Oral Presentation 3 (Online)

座長：大橋南美（昭和薬大）、伊藤幸裕（阪大産業科学研）

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9:00 AM - 9:12 AM

[27V03-am01S] Development and application of a new heme-selective fluorescent probe

○Kawai Kanta¹, Tasuku Hirayama¹, Mieko Tsuji¹, Hideko Nagasawa¹ (1. Gifu Pharm. Univ.)

9:12 AM - 9:24 AM

[27V03-am02S] Sequence-specific detection of DNA-methylation using psoralen-conjugated oligonucleotides

○Atsuhiro Kojima¹, Tsuyoshi Yamamoto¹, Naohiko Shimada², Atsushi Maruyama², Asako Yamayoshi^1,3 (1. Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Dep.of Life Sci. and Tech., Tokyo Inst. of Tech, Osaka Univ., 3. PRESTO･JST)

9:24 AM - 9:36 AM

[27V03-am03S] Development of novel photo-responsive oligonucleotides targeting epigenetic gene modifications

○Kinuka Doi¹, Chitose Hida¹, Tsuyoshi Yamamoto², Chikara Dohno³, Takehiko Wada⁴, Asako Yamayoshi^2,5 (1. Sch. Pharm. Sci., Nagasaki Univ., 2. Grad. Sch. Biomed. Sci., Nagasaki Univ., 3. Inst. of Sci. Indust.Res., Osaka Univ., 4. Inst. of Multi-discip. Res. for Adv. Mater., Tohoku Univ., 5. PRESTO･JST)

9:36 AM - 9:48 AM

[27V03-am04S] Development of a hydroxamic acid type-catalyst for protein lysine acetylation in cells

○Habazaki Misuzu¹, Hidetoshi Kajino¹, Shinsuke Mizumoto¹, Shigehiro Kawashima¹, Kenzo Yamatsugu¹, Motomu Kanai¹ (1. Grad. Sch. Pharm. Sci., The Univ. of Tokyo)

9:48 AM - 10:00 AM

[27V03-am05S] Cytosolic delivery of biomacromolecules using basic hemolytic peptide: an attempt to develop efficient delivery peptides by the substitution of aromatic amino acid residues.

○Junya Michibata¹, Kentarou Sakamoto¹, Shiroh Futaki¹ (1. Institute for Chemical Research, Kyoto University)

10:00 AM - 10:12 AM

[27V03-am06S] Design, Synthesis and Biological Evaluation of 2-Pyrrolone Derivatives for Radioprotective Agents and Investigation of Their Target Biomolecules

○Hidetoshi Satoh¹, Shintaro Ochi², Shohei Ujita², Yuichi Nishiyama², Kasumi Tada², Yosuke Matsushita^2,3, Yuichi Deguchi³, Keiji Suzuki³, Yoshimasa Tanaka³, Hiroshi Ueda³, Toshiya Inaba⁴, Yoshio Hosoi⁵, Akinori Morita², Shin Aoki^1,6 (1. Grad. Sch. Pharm. Sci., Tokyo Univ. of Sci., 2. Grad. Sch. Biomed. Sci., Tokushima Univ., 3. Dept. Pharm. Ther. Innov., Nagaski Univ., 4. Res. Inst. Rad. Biol. Med., Hiroshima Univ., 5. Dept. Rad. Biol., Tohoku Univ., 6. Res. Inst. Sci. Tech., Tokyo Univ. of Sci.)

10:12 AM - 10:24 AM

[27V03-am07S] Photo-oxygenation Catalyst for α-Synuclein towards Parkinson's Disease Treatment Strategy

○Atsushi Iwai¹, Nozomu Nagashima¹, Reito Nakamura¹, Yukiko Hori¹, Taisuke Tomita¹, Youhei Sohma¹, Motomu Kanai¹ (1. Grad. Sch. Pharm. Sci., Univ. Tokyo)

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