[27V04-am] 放射化学１

Sat. Mar 27, 2021 9:00 AM - 10:36 AM [Room V04] Oral Presentation 4 (Online)

座長：淵上剛志（長崎大院医歯薬）、渡邊裕之（京大院薬）

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9:00 AM - 9:12 AM

[27V04-am01] Influence of linker structure of multivalent RGD peptides on the interaction with integrin α_vβ₃ positive tumors

○Yuki Mizuno^1,2, Kohta Kimura², Satoru Onoe², Miho Shukuri², Yuji Kuge¹, Hiromichi Akizawa² (1. Cen. Inst. of Isot. Sci., Hokkaido Univ., 2. Showa Pharm. Univ.)

9:12 AM - 9:24 AM

[27V04-am02S] Synthesis of radioactive gallium-labeled peptide targeting ADAM8 and evaluation of its usefulness as an enzyme activity-responsive molecular probe

○Ryota Yamaguchi¹, Tsukasa Kosugi², Yusuke Miyanari³, Ayako Tagawa³, Sakura Yoshida¹, Morio Nakayama¹, Akira Toriba¹, Takeshi Fuchigami¹ (1. Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Fac. Pharm. Sci., Nagasaki Univ., 3. Scie. Ins. Nano Life, Kanazawa Univ.)

9:24 AM - 9:36 AM

[27V04-am03S] Basic evaluation for the development of ²¹¹At-labeled amino acids using neopentyl scaffolds

○Yuta Kaizuka¹, Hiroyuki Suzuki¹, Tomoya Uehara¹ (1. Grad. Sch. Med. Pharm. Sci., Chiba Univ.)

9:36 AM - 9:48 AM

[27V04-am04S] Combination of radiolabeled antibody fragment with a cleavable linkage and lysine coinjection for low renal radioactivity levels

○Koki Tatsugi¹, Hiroyuki Suzuki¹, Mari Araki¹, Tomoya Uehara¹ (1. Grad. Sch. Pharm. Sci., Chiba. Univ.)

9:48 AM - 10:00 AM

[27V04-am05S] Development of myelin imaging probes for diagnosis of multiple sclerosis : Synthesis and evaluation of radioiodinated diaryloxadiazole derivatives

○Rinka Maekawa¹, Hiroyuki Watanabe¹, Shimpei Iikuni¹, Masashi Kakae¹, Nagisa Matsuo¹, Hisashi Shirakawa¹, Shuji Kaneko¹, Masahiro Ono¹ (1. Grad. Sch. Pharm. Sci., Kyoto Univ.)

10:00 AM - 10:12 AM

[27V04-am06S] Development of novel radiotheranostic agents based on picolinic acid as metal chelator

○Yuta Tarumizu¹, Shimpei Iikuni¹, Hiroyuki Watanabe¹, Masahiro Ono¹ (1. Grad. Sch. Pharm. Sci., Kyoto Univ.)

10:12 AM - 10:24 AM

[27V04-am07] Development of novel ²²⁵Ac-labeled radiotheranostic agent targeting PSMA

○Shimpei Iikuni¹, Hiroyuki Watanabe¹, Yusuke Higaki², Hiroaki Ichikawa², Masahiro Ono¹ (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. NMP)

10:24 AM - 10:36 AM

[27V04-am08S] Synthesis and fundamental evaluation of trifunctional chelator for radiotheranostics using click chemistry.

○Kazuma Nakashima¹, Shimpei Iikuni¹, Hiroyuki Watanabe¹, Masahiro Ono¹ (1. Grad. Sch. Pharm. Sci., Kyoto Univ.)

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