Oral Presentation

[27V06-pm] 中枢神経②（神経変性）

Sat. Mar 27, 2021 1:15 PM - 3:27 PM [Room V06] Oral Presentation 6 (Online)

座長：高田和幸（京都薬大）、藤田和歌子（⻑崎⼤院医⻭薬）

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1:15 PM - 1:27 PM

[27V06-pm01S] Assessment of paraquat toxicity for nigral dopaminergic neurodegeration

○Haruna Tamura¹, Ryusuke Nishio¹, Nana Saeki¹, Misa Katahira¹, Hiroki Morioka¹, Haruna Tamano¹, Atsushi Takeda¹ (1. Sch. Pharm. Sci., Univ. Shizuoka)

1:27 PM - 1:39 PM

[27V06-pm02S] Preventive effect of Ninjin-yoei-to, a Japanese herbal medicine, against hippocampal neurodegeneration by amyloid β_1-42-induced Zn²⁺ toxicity

○Yuka Nishijima¹, Haruna Tokoro¹, Erina Tuda¹, Daichi Murakami¹, Haruna Tamano¹, Atsushi Takeda¹ (1. Sch.Pharm.Sci.,Univ.Shizuoka)

1:39 PM - 1:51 PM

[27V06-pm03S] Comparative study on neurotoxic mechanism between amyloid β_1-40 and amyloid β_1-42and preventive effect of Ninjin-yoei-to, a Kampo medicine

○Erina Tsuda¹, Yuka Nishijima¹, Daichi Murakami¹, Haruna Tokoro¹, Haruna Tamano¹, Atsushi Takeda¹ (1. Sch.Pharm.Sci.,Univ.Shizuoka)

1:51 PM - 2:03 PM

[27V06-pm04S] Adrenergic β receptor activation rescues attenuation of dentate gyrus LTP by reducing amyloid β_1-42-induced intracellular Zn²⁺ toxicity in the hippocampus

○Rin Tsujimoto¹, Yudai Ishikawa², Ryusei Itoh¹, Haruna Tamano^1,2, Atsushi Takeda^1,2 (1. Sch. Pharm. Sci., Univ. Shizuoka, 2. Grad. Sch. Pharm. Sci., Univ. Shizuoka)

2:03 PM - 2:15 PM

[27V06-pm05S] Suppression of hippocampal neurodegeneration via amyloid β_1-42-mediated intracellular Zn²⁺ toxicity by adrenergic β receptor activation

○Yuya Kawano¹, Mako Egawa¹, Kotaro Tamura¹, Haruna Tamano¹, Atsushi Takeda¹ (1. Sch.Pharm.Sci.,Univ.Shizuoka)

2:15 PM - 2:27 PM

[27V06-pm06S] Defense strategy against amyloid β_1-42-induced hippocampal neurodegeneration by metallothionein induction

○Daichi Murakami¹, Yukino Tanaka¹, Haruna Tokoro¹, Haruna Tamano¹, Atushi Takeda¹ (1. Sch. Pharm., Univ Shizuoka)

2:27 PM - 2:39 PM

[27V06-pm07S] Panaxytriol suppresses activated microglia in a mouse model of braini nflammation induced by LPS

○Genki Hiramatsu¹, Kosuke Matsuda², Daisuke Uta¹, Kenichi Mihara³, Tsugunobu Andoh⁴, Toshiaki Kume¹ (1. Grad. Sch. Med & Pharmaceut Sci., Toyama Univ., 2. Dept. Pharmaceut Sci., Toyama Univ., 3. KIM's Korean Ginseng Co. Ltd., 4. Dept. Pharmaceut Sci., Kinjo Gakuin Univ.)

2:39 PM - 2:51 PM

[27V06-pm08] Effect of PRDX6 on the production of inflammatory cytokine and GLT-1 expression in cultured astrocytes

○Akiko Yamamuro¹, Chihiro Aki¹, Hiroki Taniguchi¹, Akane Sumi¹, Yuki Ishimaru¹, Yasuhiro Yoshioka¹, Sadaaki Maeda¹ (1. Faculty of Pharmaceutical Sciences Setsunan University)

2:51 PM - 3:03 PM

[27V06-pm09S] Identification of scavenger inducing factor for the accelerated removal of inflammatogenic DAMPs

○Kento Otani^1,2, Jun Tsuyama¹, Koji Hase², Takashi Shichita¹ (1. Stroke Renaissance Project, Tokyo Met. Inst. of Med. Sci., 2. Dept. Biochem., Grad. Sch. of Pharmaceutical Sci., Keio Univ.)

3:03 PM - 3:15 PM

[27V06-pm10S] Effects of anti-interleukin-6 receptor antibody on mechanical hypersensitivity and cognitive dysfunction in mice with neuropathic pain

○Kodai Moriwaki¹, Kazue Hisaoka-Nakashima², Toshiki Yoshi¹, Yoki Nakamura², Norimitsu Morioka² (1. Sch. Pharm. Sci., Hiroshima Univ., 2. Grad. Sch. Biomed. Health Sci., Hiroshima Univ.)

3:15 PM - 3:27 PM

[27V06-pm11] The effects of dimethyl fumarate and monomethyl fumarate on the NMDA-induced neurotoxicixity
in the murine retina.

○Kenji Sakamoto¹, Erika Muta¹, Takashi Uezono¹, Junichi Kurihara¹ (1. Fac. Pharma-Sci., Teikyo Univ.)

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