オーガナイザー挨拶：吉田 小莉（星薬大） (1:15 PM - 1:20 PM)
Session information
Symposium
[GS03] Latest research on next-generation "neuro-immunology": multiangle approaches in the CNS and glia cells
Sun. Mar 28, 2021 1:15 PM - 3:15 PM [Room C] Oral Presentation C (Online)
Organizer: Yoshida Sara (Hoshi Univ.), Kohno Keita (Grad. Sch. Pharmaceut. Sci. Kyushu. Univ.)
In general, various external stimuli associated with excess stress and chronic pain induce synaptic plasticity and dysfunction of both the central nervous system (CNS) and glial cells (astrocytes and microglia). Abnormality of the neural network and/or glial cells triggers various disease-based phenotypes, such as psychiatric disorders, persistent pain, dementia and immunodeficiency. On the other hand, it has been suggested that dysfunction of the CNS leads to peripheral symptoms through various efferent controls. However, the causal relationship between synaptic plasticity and peripheral phenomena, such as chronic pain and immunodeficiency, has not yet been clarified. To investigate these mechanisms, it is crucial that we understand “neuro-immunity” mediated by neural and glial functions. In this symposium, we will introduce the latest research on “neuro-immunity” derived from dysfunction of the CNS and glial cells, which is associated with various diseases. We hope that our discussions will provide the audience insights that could lead to the discovery of new treatments.
1:20 PM - 1:42 PM
[GS03-1] Pathological mechanism of autoimmune encephalomyelitis regulated by vagus nerve innervation
○Steve So Mansfield1,2, Shogo Tanabe1, Rieko Muramatsu1 (1. NCNP, 2. Tokyo Med. & Dent. Univ. Grad. Sch. Med. & Dent. Sci.)
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1:42 PM - 2:04 PM
○Iyo Yorifuji1, Hiroshi Tsujioka1, Yasushi Sakata1, Toshihide Yamashita1 (1. Osaka Univ. Medicine)
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2:04 PM - 2:26 PM
○Keita Kohno1, Makoto Tsuda1 (1. Grad. Sch. Pharmaceut. Sci. Kyushu. Univ.)
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2:26 PM - 2:48 PM
○Yuka Ishikawa1,2, Shiho Kitaoka1, Taro Kato2, Tomoyuki Furuyashiki1 (1. Grad. Sch. of Med., Kobe Univ., 2. Sumitomo Dainippon Pharm)
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2:48 PM - 3:10 PM
○Sara Yoshida1, Yusuke Hamada1,4, Shuhei Yabe1, Daisuke Sato1, Michiko Narita2,4, Akihiro Yamanaka3, Naoko Kuzumaki1, Minoru Narita1,4 (1. Hoshi Univ., 2. IMS, Tokyo Med. Univ., 3. RIEM, Nagoya Univ., 4. NCCRI)
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総括：河野 敬太（九大院薬） (3:10 PM - 3:15 PM)