[S29] Recent progress in partnerships for NTD drug discovery in 2021

Sun. Mar 28, 2021 3:45 PM - 5:45 PM [Room F] Oral Presentation F (Online)

Organizer: Yamada Haruki, Nozaki Tomoyoshi (Grad. Sch. Med., Fac. Med., Univ. of Tokyo)

Neglected tropical diseases (NTDs), which expose about one-sixth of the world’s population to infection, are poorly marketable and existing drug development mechanisms do not work due to the high prevalence of patients in poorer areas of developing countries. DNDi is one of the not-for-profit international Product Development Partnership (PDP) based in Geneva established in 2003 to solve these problems and efficiently promoting research and development of NTDs drugs at all stages which meet the needs of endemic areas with industry-government-academia partners around the globe.
Academia and pharmaceutical companies are not doing anything. Original technologies and know-how that can be used to treat NTDs are constantly being created. However, academia has major hurdles to bring candidate compounds to the clinical phase, while most pharmaceutical companies no longer consider infectious diseases to be their main business area. Hence, PDP, which connects partners’ areas of expertise to manage projects and raise funds, provides a solution for NTDs drug discovery.
At this symposium, we will report the achievements and future development of the “NTD Drug Discovery Booster” that has been implemented with GHIT support since 2015, and the game-changing partnerships of industry-academia-government for new drug discovery and are happy to discuss the expected role of Japan in future drug discovery for NTDs.

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オーガナイザー挨拶：山田陽城^1,2（1. DNDi Japan，2. 北里大） (3:45 PM - 3:50 PM)

3:50 PM - 4:08 PM

[S29-1] NTD Drug Discovery Booster, achievements and next steps

○Tatsuro Kuzuki¹, Perry Benjamin¹, Charles Mowbray¹ (1. DNDi)

4:08 PM - 4:26 PM

[S29-2] Corporate efforts to research and develop therapeutic agents for infectious diseases that threaten human

○Ryu Yoshida¹, Rina Kaki¹, Osamu Yoshida¹, Takao Shishido¹, Teruhisa Kato¹, Yoshinori Yamano¹ (1. SHIONOGI & Co., LTD.)

4:26 PM - 4:44 PM

[S29-3] Partnership Activity for Neglected Tropical Diseases

○Yuichiro Akao¹, Atsuko Ochida¹, Hiroya Muranishi¹, Izumi Nomura¹, Takashi Ichikawa¹ (1. Takeda Pharmaceutical Company)

4:44 PM - 5:02 PM

[S29-4] A Strategic Partnership for the Medicine Creation and Provision against Neglected Tropical Diseases

○Katsura Hata¹ (1. Eisai)

5:02 PM - 5:20 PM

[S29-5] Nucleic acid-based Immuno-prophylaxis and -therapies against tropical diseases

○Ken Ishii^1,2 (1. Institute of Medical Science U Tokyo, 2. Institute of Biomedical Innovation, Health and Nutrition)

5:20 PM - 5:38 PM

[S29-6] Introduction of Astellas' "Access to Health" initiatives for Neglected Tropical Diseases (NTDs) ~R&D of NTD medicines~

○Fumiya Domoto¹ (1. Astellas Pharma Inc.)

質疑応答 (5:38 PM - 5:40 PM)

総括：野崎智義（東大院医） (5:40 PM - 5:45 PM)